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L W Enquist

Explore the profile of L W Enquist including associated specialties, affiliations and a list of published articles. Areas
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Articles 147
Citations 6096
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Recent Articles
11.
Szpara M, Tafuri Y, Enquist L
J Vis Exp . 2011 Aug; (54). PMID: 21876519
Viruses are obligate cellular parasites, and thus the study of their DNA requires isolating viral material away from host cell contaminants and DNA. Several downstream applications require large quantities of...
12.
Kramer T, Greco T, Enquist L, Cristea I
J Virol . 2011 Apr; 85(13):6427-41. PMID: 21525350
Pseudorabies virus (PRV), a member of the Alphaherpesvirinae, has a complex multilayered extracellular virion that is structurally conserved among other herpesviruses. PRV virions contain a double-stranded DNA genome within a...
13.
Szpara M, Parsons L, Enquist L
J Virol . 2010 Mar; 84(10):5303-13. PMID: 20219902
Herpes simplex virus 1 (HSV-1) is a well-adapted human pathogen that can invade the peripheral nervous system and persist there as a lifelong latent infection. Despite their ubiquity, only one...
14.
Lyman M, Kemp C, Taylor M, Enquist L
J Virol . 2009 May; 83(14):6978-86. PMID: 19420087
Pseudorabies virus (PRV) Us9 is a small, tail-anchored (TA) membrane protein that is essential for axonal sorting of viral structural proteins and is highly conserved among other members of the...
15.
Enquist L
J Virol . 2009 Mar; 83(11):5296-308. PMID: 19297504
No abstract available.
16.
Curanovic D, Lyman M, Bou-Abboud C, Card J, Enquist L
J Virol . 2008 Nov; 83(3):1173-83. PMID: 19019952
The attenuated pseudorabies virus (PRV) strain Bartha contains several characterized mutations that affect its virulence and ability to spread through neural circuits. This strain contains a small genomic deletion that...
17.
Lyman M, Curanovic D, Brideau A, Enquist L
J Virol . 2008 Aug; 82(20):10308-11. PMID: 18684822
Pseudorabies virus encodes a membrane protein (Us9) that is essential for the axonal sorting of virus particles within neurons and anterograde spread in the mammalian nervous system. Enhanced green fluorescent...
18.
Liu W, Goodhouse J, Jeon N, Enquist L
PLoS One . 2008 Jun; 3(6):e2382. PMID: 18560518
Alpha-herpesviruses, including herpes simplex virus and pseudorabies virus (PRV), infect the peripheral nervous system (PNS) of their hosts. Here, we describe an in vitro method for studying neuron-to-cell spread of...
19.
Card J, Enquist L
Curr Protoc Neurosci . 2008 Apr; Chapter 1:Unit1.5. PMID: 18428451
Over the past decade there has been a dramatic increase in the use of viruses as transneuronal tracers of neuronal circuitry. The method exploits the propensity of neurotropic viruses to...
20.
Ekstrand M, Enquist L, Pomeranz L
Trends Mol Med . 2008 Feb; 14(3):134-40. PMID: 18280208
Several neuroinvasive viruses can be used to study the mammalian nervous system. In particular, infection by pseudorabies virus (PRV), an alpha-herpesvirus with broad host range, reveals chains of functionally connected...