L W Chamley
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Explore the profile of L W Chamley including associated specialties, affiliations and a list of published articles.
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68
Citations
1107
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Recent Articles
1.
Nursalim Y, Groom K, Blenkiron C, Chamley L
Placenta
. 2021 Mar;
108:1-10.
PMID: 33780666
Introduction: Primary trophoblast cultures obtained from term placentae are an important research tool. Term trophoblasts, while isolated as mononuclear cells, spontaneously fuse to form multinucleated syncytial clusters. Since term trophoblast...
2.
Abumaree M, Almutairi A, Cash S, Boeuf P, Chamley L, Gamage T, et al.
Placenta
. 2016 Aug;
48 Suppl 1:S17-S20.
PMID: 27506263
Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialised topics. At the 2015 IFPA annual meeting there were 12 themed workshops, three...
3.
Wei J, Lau S, Blenkiron C, Chen Q, James J, Kleffmann T, et al.
Sci Rep
. 2016 Jul;
6:30632.
PMID: 27468655
The mechanisms by which the fetus induces maternal physiological adaptations to pregnancy are unclear. Cellular debris, shed from the placental syncytiotrophoblast into the maternal blood and phagocytosed by maternal endothelial...
4.
Tong M, Brown O, Stone P, Cree L, Chamley L
Placenta
. 2016 Feb;
38:29-32.
PMID: 26907379
Nanoparticle tracking analysis (NTA) is commonly used to count and size nano-sized particles. A sample loading pump can be used to analyse a larger sample volume, but it is unclear...
5.
Wei J, Chen Q, James J, Stone P, Chamley L
Placenta
. 2015 Oct;
36(12):1385-92.
PMID: 26515928
Introduction: Necrotic but not apoptotic trophoblastic debris can induce endothelial cell activation but the mechanism by which endothelial cells distinguish apoptotic from necrotic debris is unclear. The NALP3 inflammasome is...
6.
Isolation and characterisation of a novel trophoblast side-population from first trimester placentae
James J, Hurley D, Gamage T, Zhang T, Vather R, Pantham P, et al.
Reproduction
. 2015 Aug;
150(5):449-62.
PMID: 26248480
The placenta is responsible for all nutrient and gas exchange between mother and baby during pregnancy. The differentiation of specialised placental epithelial cells called trophoblasts is essential for placental function,...
7.
Chen Q, Zhao M, Guo F, Yin Y, Xiao J, Stone P, et al.
Placenta
. 2015 Apr;
36(6):661-6.
PMID: 25907222
Introduction: Women with preeclampsia have elevated levels of inflammatory cytokines including IL-6. IL-6, which is known to activate endothelial cells and induce the production of necrotic trophoblastic debris from the...
8.
Tong M, Viall C, Chamley L
Hum Reprod Update
. 2015 Feb;
21(3):407.
PMID: 25646210
No abstract available.
9.
Tong M, Chamley L
Cold Spring Harb Perspect Med
. 2015 Jan;
5(3):a023028.
PMID: 25635060
The human placenta is an anatomically unique structure that extrudes a variety of extracellular vesicles into the maternal blood (including syncytial nuclear aggregates, microvesicles, and nanovesicles). Large quantities of extracellular...
10.
Tong M, Viall C, Chamley L
Hum Reprod Update
. 2014 Sep;
21(1):97-118.
PMID: 25228006
Background: Antiphospholipid antibodies (aPL) are a family of auto-antibodies that are associated with an increased risk of recurrent miscarriage, intrauterine growth restriction and preterm birth. The placenta is a major...