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L Velisek

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Articles 70
Citations 402
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Recent Articles
1.
Friedman L, Kahen B, Velisek L, Veliskova J
Brain Res . 2022 Mar; 1783:147849. PMID: 35231419
Chronic subconvulsive activity in early life leads to sex-related autistic-like deficits in handling, object recognition, and social performance in pre-pubertal rats. Since autism and epilepsy are common neurodevelopmental disorders with...
2.
Veliskova J, Iacobas D, Iacobas S, Sidyelyeva G, Chachua T, Velisek L
J Neuroendocrinol . 2015 Nov; 27(12):911-20. PMID: 26541912
Neuropeptide Y (NPY) is an endogenous modulator of neuronal activity affecting both GABAergic and glutamatergic transmission. Previously, we found that oestradiol modifies the number of NPY immunoreactive neurones in the...
3.
Chachua T, Goletiani C, Maglakelidze G, Sidyelyeva G, Daniel M, Morris E, et al.
Genes Brain Behav . 2014 Aug; 13(7):702-12. PMID: 25130458
Idiopathic generalized epilepsy represents about 30-35% of all epilepsies in humans. The bromodomain BRD2 gene has been repeatedly associated with the subsyndrome of juvenile myoclonic epilepsy (JME). Our previous work...
4.
Iacobas D, Iacobas S, Chachua T, Goletiani C, Sidyelyeva G, Veliskova J, et al.
J Neuroendocrinol . 2013 Jun; 25(11):964-79. PMID: 23763471
Prenatal exposure to corticosteroids has long-term postnatal somatic and neurodevelopmental consequences. Animal studies indicate that corticosteroid exposure-associated alterations in the nervous system include hypothalamic function. Infants with infantile spasms, a...
5.
Velisek L, Mares P
Physiol Res . 2004 Aug; 53(4):453-61. PMID: 15312006
Hippocampal afterdischarges (ADs) are considered to be a model of complex partial seizures. To study the pharmacology of these ADs, stimulation electrodes were implanted into the dorsal hippocampus of 33...
6.
Velisek L, Moshe S
Epilepsia . 2003 Dec; 44 Suppl 12:51-9. PMID: 14641561
The origins of human mesial temporal lobe epilepsy and hippocampal sclerosis are still not well understood. Hippocampal sclerosis and temporal lobe epileptogenesis involve a series of pathologies including hippocampal neuronal...
7.
Kabova R, Velisek L
Brain Res Dev Brain Res . 2000 Oct; 123(1):91-4. PMID: 11020554
We determined the effects of prenatal exposure to DNA synthesis inhibitor methotrexate (MTX) on: (a) the susceptibility to low Mg(2+)-induced epileptiform activity in deep layers (IV-V) of medial entorhinal cortex...
8.
Claudio O, Ferchmin P, Velisek L, Sperber E, Moshe S, Ortiz J
Epilepsia . 2000 Sep; 41 Suppl 6:S104-10. PMID: 10999530
Purpose: To examine the relationship between seizures and excitatory amino acid transporter (EAAT) activity and whether up-regulation of EAAT activity alters epileptogenicity. Methods: In this study, we exposed rat hippocampal...
9.
Veliskova J, Velisek L, Galanopoulou A, Sperber E
Epilepsia . 2000 Sep; 41 Suppl 6:S30-5. PMID: 10999516
Purpose: Estrogens have neuroprotective effects in ischemia, stroke, and other conditions leading to neuronal cell death (e.g., Alzheimer's disease). The present study examined whether estrogens may have neuroprotective effects after...
10.
Liptakova S, Velisek L, Veliskova J, Moshe S
Epilepsia . 2000 Jul; 41(7):788-93. PMID: 10897148
Purpose: To determine the effects of a newly synthesized epalon, ganaxolone (GNX), on primarily generalized seizures in rats of various ages during development. Epalons are classified as neuroactive steroids that...