L V McIntire
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Explore the profile of L V McIntire including associated specialties, affiliations and a list of published articles.
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3101
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Recent Articles
1.
GPIbα-vWF rolling under shear stress shows differences between type 2B and 2M von Willebrand disease
Coburn L, Damaraju V, Dozic S, Eskin S, Cruz M, McIntire L
Biophys J
. 2011 Jan;
100(2):304-12.
PMID: 21244826
Both type 2B and type 2M von Willebrand disease result in bleeding disorders; however, whereas type 2B has increased binding affinity between platelet glycoprotein Ibα and von Willebrand factor (vWF),...
2.
Patrick Jr C, McIntire L
Trends Cardiovasc Med
. 2011 Jan;
6(4):122-9.
PMID: 21232285
Bioengineers and vascular biologists have enjoyed a successful symbiosis over the last two decades. In particular, bioengineers and life scientists have begun to understand the cellular and molecular mechanisms that...
3.
Patrick C, McIntire L
Tissue Eng
. 2009 Nov;
1(1):53-70.
PMID: 19877915
Fluid flow can modulate endothelial cell intracellular pH (pH(i)). Venous and arterial shear stresses of 1.4 and 14 dyn/cm2, respectively, induced intracellular acidification. The kinetics of the process and magnitude...
4.
Kao S, Turner N, Moake J, McIntire L
J Thromb Haemost
. 2003 Jul;
1(2):347-54.
PMID: 12871510
Under flow conditions, platelets adhere singly or in small aggregates on von Willebrand factor (VWF)-coated surfaces, but form large aggregates on immobilized fibrillar collagen. We developed a novel flow cytometric...
5.
Dong J, Li C, Schade A, Sun L, McIntire L, Lopez J
Zhonghua Xue Ye Xue Za Zhi
. 2002 Mar;
21(9):453-6.
PMID: 11877016
Objective: To study the importance of glycoprotein (GP) I balpha mutation (A156V) in interaction between mutant expressing cell and immobilized vWF under fluid shear stress. Methods: Mutant GP I balpha...
6.
Dong J, Li C, Schade A, Fredrickson B, Sun L, McIntire L, et al.
Chin Med J (Engl)
. 2002 Jan;
113(8):693-8.
PMID: 11776050
Objective: To characterize effects of the GP Ib alpha mutation (A156V) on its interaction with von Willebrand factor (vWf) under high fluid shear stress. Methods: The residue A156 of GP...
7.
Stamatas G, McIntire L
Ind Eng Chem Res
. 2002 Jan;
38(3):601-9.
PMID: 11757568
For the last 3 decades evidence has been accumulating that some types of mammalian cells respond to their mechanically active environment by altering their morphology, growth rate, and metabolism. The...
8.
Turner N, Moake J, McIntire L
Blood
. 2001 Nov;
98(12):3340-5.
PMID: 11719372
Using heparinized whole blood and flow conditions, it was shown that adenosine 5'-diphosphate (ADP) receptors P2Y(12) and P2Y(1) are both important in direct shear-induced platelet aggregation and platelet aggregation subsequent...
9.
Nguyen K, Frye S, Eskin S, Patterson C, Runge M, McIntire L
Hypertension
. 2001 Nov;
38(5):1038-43.
PMID: 11711494
Cyclic strain regulates many vascular smooth muscle cell (VSMC) functions through changing gene expression. This study investigated the effects of cyclic strain on protease-activated receptor-1 (PAR-1) expression in VSMCs and...
10.
Seo S, McIntire L, Smith C
Am J Physiol Cell Physiol
. 2001 Oct;
281(5):C1568-78.
PMID: 11600420
Firm adhesion of rolling neutrophils on inflamed endothelium is dependent on beta(2) (CD18)-integrins and activating stimuli. LFA-1 (CD11a/CD18) appears to be more important than Mac-1 (CD11b/CD18) in neutrophil emigration at...