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L Sorokin

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Articles 36
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Recent Articles
11.
Voit T, Cohn R, Sperner J, Leube B, Sorokin L, Toda T, et al.
Neuromuscul Disord . 1999 Apr; 9(2):95-101. PMID: 10220864
The congenital muscular dystrophies (CMDs) are a heterogeneous group of disorders. Among these, the laminin alpha 2 chain 'merosin' deficient CMD is caused by mutations of the LAMA2 gene on...
12.
Gu Y, Sorokin L, Durbeej M, Hjalt T, Jonsson J, Ekblom M
Blood . 1999 Apr; 93(8):2533-42. PMID: 10194432
Laminins are extracellular matrix glycoproteins that influence the phenotype and functions of many types of cells. Laminins are heterotrimers composed of alpha, beta, and gamma polypeptides. So far five alpha,...
13.
Morandi L, Di Blasi C, Farina L, Sorokin L, Uziel G, Azan G, et al.
Arch Neurol . 1999 Feb; 56(2):209-15. PMID: 10025426
Background: Many patients with classic congenital muscular dystrophy have been found to have partial or total deficiency of the alpha2 chain of laminin 2 (merosin). This deficiency has mostly been...
14.
Ringelmann B, Roder C, Hallmann R, Maley M, Davies M, Grounds M, et al.
Exp Cell Res . 1999 Jan; 246(1):165-82. PMID: 9882526
The dy/dy mouse is an animal model for human merosin-negative congenital muscular dystrophy (CMD), which has been reported to have reduced or no expression of the basement membrane protein laminin...
15.
Cohn R, Herrmann R, Sorokin L, Wewer U, Voit T
Neurology . 1998 Jul; 51(1):94-100. PMID: 9674785
Objective: To characterize the expression of distinct fragments of laminin alpha2 chain in patients with partial laminin alpha2 chain deficiency and variable clinical severity. Background: Deficiency of laminin alpha2 chain...
16.
Sewry C, Uziyel Y, Torelli S, Buchanan S, Sorokin L, Cohen J, et al.
Neuropathol Appl Neurobiol . 1998 Apr; 24(1):66-72. PMID: 9549731
Laminin alpha 2, a sub-unit of the basement membrane component laminin-2, is deficient in the dy/dy and allelic dy2 J/dy2 J mouse. It is also the defective protein in a...
17.
Schuger L, Skubitz A, Zhang J, Sorokin L, He L
J Cell Biol . 1997 Oct; 139(2):553-62. PMID: 9334356
Laminins, the main components of basement membranes, are heterotrimers consisting of alpha, beta, and gamma polypeptide chains linked together by disulfide bonds. Laminins-1 and -2 are both composed of beta1...
18.
Sewry C, Naom I, dAlessandro M, Sorokin L, Bruno S, Wilson L, et al.
Neuromuscul Disord . 1997 May; 7(3):169-75. PMID: 9185180
Approximately half the cases of classical congenital muscular dystrophy (CMD) have a pronounced deficiency or absence of the laminin alpha 2 chain of laminin-2 (merosin). This is caused by mutations...
19.
Weismann M, Guse A, Sorokin L, Broker B, Frieser M, Hallmann R, et al.
J Immunol . 1997 Feb; 158(4):1618-27. PMID: 9029097
T lymphocytes interact with components of the extracellular matrix after transendothelial migration on their way to sites of inflammation. To characterize the molecular basis of the interaction between T lymphocytes...
20.
Durbeej M, Fecker L, Hjalt T, Zhang H, Salmivirta K, Klein G, et al.
Matrix Biol . 1996 Dec; 15(6):397-413. PMID: 9049978
Laminins, found predominantly in basement membranes, are large glycoproteins consisting of different subsets of alpha, beta and gamma chain subunits. To resolve conflicting data in the literature concerning coexpression of...