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» Authors » L Serghides

L Serghides

Explore the profile of L Serghides including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 5
Citations 176
Followers 0
Related Specialties
Hematology
Gynecology & Obstetrics
Biomedical Engineering
Top 10 Co-Authors
K C Kain
L S Cahill
J G Sled
N Milligan
M Guzman Lenis
A Kapus
I D McGilvray
S Shinar
A Ravi Chandran
I Crandall
Published In
Blood
Ultrasound Obstet Gynecol
J Immunol
EBioMedicine
Affiliations
Soon will be listed here.
Recent Articles
1.
Peripheral cord insertion is associated with adverse pregnancy outcome only when accompanied by clinically significant placental pathology
Stapleton D, Darmonkow A, Ravi Chandran A, Milligan N, Saghian R, Shinar S, et al.
Ultrasound Obstet Gynecol . 2023 Mar; 62(2):248-254. PMID: 36971026
Objective: To examine the relationship between umbilical cord insertion site, placental pathology and adverse pregnancy outcome in a cohort of normal and complicated pregnancies. Methods: Sonographic measurement of the cord...
2.
In response to the Letter to the Editor by Romach et al. re our publication "Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not at supratherapeutic levels"
Mohan H, Guzman Lenis M, Laurette E, Tejada O, Sanghvi T, Leung K, et al.
EBioMedicine . 2021 Apr; 66:103334. PMID: 33862586
No abstract available.
3.
Peroxisome proliferator-activated receptor gamma-retinoid X receptor agonists increase CD36-dependent phagocytosis of Plasmodium falciparum-parasitized erythrocytes and decrease malaria-induced TNF-alpha secretion by monocytes/macrophages
Serghides L, Kain K
J Immunol . 2001 May; 166(11):6742-8. PMID: 11359831
Severe and fatal malaria is associated with the failure of host defenses to control parasite replication, excessive secretion of proinflammatory cytokines such as TNF-alpha, and sequestration of parasitized erythrocytes (PEs)...
4.
Nonopsonic monocyte/macrophage phagocytosis of Plasmodium falciparum-parasitized erythrocytes: a role for CD36 in malarial clearance
McGilvray I, Serghides L, Kapus A, Rotstein O, Kain K
Blood . 2000 Oct; 96(9):3231-40. PMID: 11050008
Plasmodium falciparum is the most lethal form of malaria and is increasing both in incidence and in its resistance to antimalarial agents. An improved understanding of the mechanisms of malarial...
5.
The Plasmodium falciparum-CD36 interaction is modified by a single amino acid substitution in CD36
Serghides L, Crandall I, HULL E, Kain K
Blood . 1998 Aug; 92(5):1814-9. PMID: 9716613
CD36 is an 88-kD glycoprotein involved in the cytoadherence of Plasmodium falciparum-parasitized erythrocytes (PE) to endothelial cells. The molecular mechanisms involved in CD36-dependent cytoadherence were examined by expressing three CD36...