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L M Shaddox

Explore the profile of L M Shaddox including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 243
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Recent Articles
1.
Branco-de-Almeida L, Velsko I, de Oliveira I, de Oliveira R, Shaddox L
J Dent Res . 2023 Feb; 102(5):473-488. PMID: 36803061
Grade C periodontitis in young individuals is characterized by severe/rapid periodontal destruction, usually early onset, in systemically healthy individuals. An individual's host response, triggered by a dysbiotic subgingival biofilm, has...
2.
Ioannidou E, Letra A, Shaddox L, Teles F, Ajiboye S, Ryan M, et al.
Adv Dent Res . 2019 Nov; 30(3):69-77. PMID: 31746653
Gender inequality in science, medicine, and dentistry remains a central concern for the biomedical research workforce today. Although progress in areas of inclusivity and gender diversity was reported, growth has...
3.
Harris T, Wallace M, Huang H, Li H, Shaddox L
JDR Clin Trans Res . 2019 Jul; 4(4):342-351. PMID: 31319038
Aim: The purpose of this study was to test for the role of the P2X7 receptor in localized aggressive periodontitis (LAP). Methods: Peripheral blood was obtained from 95 subjects with...
4.
Goncalves P, Harris T, Elmariah T, Aukhil I, Wallace M, Shaddox L
J Periodontal Res . 2017 Nov; 53(2):164-173. PMID: 29105764
Aggressive periodontitis is a rare but rapidly progressing form of periodontal disease that usually affects otherwise systemically healthy individuals, at a young age. It usually affects first molars and incisors,...
5.
Shaddox L, Mullersman A, Huang H, Wallet S, Langaee T, Aukhil I
Clin Epigenetics . 2017 Sep; 9:94. PMID: 28883894
Background: We have previously demonstrated a Toll-like receptor (TLR)-mediated hyper-responsive phenotype in our cohort of localized aggressive periodontitis (LAP) individuals. However, mechanisms related to this phenotype are still not clear...
6.
Branco-de-Almeida L, Cruz-Almeida Y, Gonzalez-Marrero Y, Huang H, Aukhil I, Harrison P, et al.
JDR Clin Trans Res . 2017 Sep; 2(3):258-268. PMID: 28879248
Localized aggressive periodontitis (LAP) patients possess a systemic hyperinflammatory response after lipopolysaccharide stimulation. However, the levels of inflammatory and bone biomarkers in plasma, as well as possible associations between local...
7.
Velsko I, Cruz-Almeida Y, Huang H, Wallet S, Shaddox L
J Oral Microbiol . 2017 Jul; 9(1):1330645. PMID: 28748035
Localized aggressive periodontitis (LAP) is a rare form of periodontal disease with site-specific rapid tissue destruction. A lipopolysaccharide (LPS) hyper-inflammatory response was shown in LAP using peripheral whole blood, although...
8.
Rody Jr W, Elmaraghy S, McNeight A, Chamberlain C, Antal D, Dolce C, et al.
Orthod Craniofac Res . 2016 Sep; 19(4):198-208. PMID: 27647720
Objectives: To test the following two hypotheses: 1) different types of retainers result in distinct levels of biomarkers in gingival crevicular fluid (GCF) and 2) the retainer bonded to all...
9.
Allin N, Cruz-Almeida Y, Velsko I, Vovk A, Hovemcamp N, Harrison P, et al.
J Dent Res . 2016 Feb; 95(6):635-41. PMID: 26917438
We previously reported a systemic hyperinflammatory response to bacterial lipopolysaccharide (LPS) in children with localized aggressive periodontitis (LAP). Additionally, different levels of this response were observed within the LAP group....
10.
Kalash D, Vovk A, Huang H, Aukhil I, Wallet S, Shaddox L
Pediatr Dent . 2015 Nov; 37(5):35-40. PMID: 26531074
Purpose: A previous study has shown that children with localized aggressive periodontitis (LAP) demonstrate a lipopolysaccharide (LPS) hyper-responsiveness in addition to elevated levels of systemic LPS when compared to periodontally...