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L M Looi

Explore the profile of L M Looi including associated specialties, affiliations and a list of published articles. Areas
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Articles 139
Citations 376
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Recent Articles
1.
Ihsan N, Sani S, Looi L, Pathmanathan D, Cheah P, Chiew S, et al.
Biophys Chem . 2024 Nov; 316:107349. PMID: 39546937
Amyloid diseases are characterized by the accumulation of misfolded protein aggregates in human tissues, pose significant challenges for both diagnosis and treatment. Protein aggregations known as amyloids are linked to...
2.
Chiew S, Toh Y, Looi L, Cheah P
Malays J Pathol . 2023 Dec; 45(3):473-478. PMID: 38155388
Jejunal diverticulosis is uncommon and so are gastrointestinal stromal tumours (GIST) arising in the jejunum. GIST arising in a jejunal diverticulum is a rarity and to date there are only...
3.
Chiew S, Looi L, Cheah P, Teoh K, Chang S, Sani S
Malays J Pathol . 2023 Dec; 45(3):363-374. PMID: 38155378
Epithelial-mesenchymal transition (EMT) is increasingly explored in cancer progression. Considering that triple negative (TN) breast cancer has the poorest survival among molecular subtypes, we investigated 49 TN, 45 luminal and...
4.
Ihsan N, Sani S, Looi L, Pathmanathan D, Cheah P, Chiew S, et al.
Spectrochim Acta A Mol Biomol Spectrosc . 2023 Dec; 308:123743. PMID: 38113556
Trace and minor elements play crucial roles in a variety of biological processes, including amyloid fibrils formation. Mechanisms include activation or inhibition of enzymatic reactions, competition between elements and metal...
5.
Ihsan N, Sani S, Looi L, Cheah P, Chiew S, Pathmanathan D, et al.
Prog Biophys Mol Biol . 2023 Jun; 182:59-74. PMID: 37307955
Amyloidosis is a deleterious condition caused by abnormal amyloid fibril build-up in living tissues. To date, 42 proteins that are linked to amyloid fibrils have been discovered. Amyloid fibril structure...
6.
Kong P, Looi L, Cheah P
Malays J Pathol . 2023 Apr; 45(1):51-63. PMID: 37119246
Introduction: Telomeres shorten with cell cycling but are restored above mortality threshold in many cancers making them potentially exploitable for differentiating malignant from benign tissues, and for cancer evaluation. Materials...
7.
Tham J, Looi L, Ghazali R
Malays J Pathol . 2023 Jan; 44(3):469-475. PMID: 36591714
Introduction: Patients who are suspected of having prostate cancer from screening tests require a tissue biopsy to confirm the presence of cancer. This study aims to compare the cost and...
8.
Wong Y, Abu Backer F, Tan G, Looi L, Mat Salleh M, A Subramaniam P, et al.
Malays J Pathol . 2022 Aug; 44(2):165-176. PMID: 36043580
No abstract available.
9.
Cheah P, Chau Y, Looi L
Malays J Pathol . 2021 Dec; 43(3):353-359. PMID: 34958056
Introduction: Immunohistochemistry (IHC) was commenced in 1986 at the Department of Pathology, University of Malaya Medical Centre, Kuala Lumpur and its usage has grown for the past 30 over years,...
10.
Sabtu S, Sani S, Looi L, Chiew S, Pathmanathan D, Bradley D, et al.
Sci Rep . 2021 Feb; 11(1):3250. PMID: 33547362
The epithelial-mesenchymal transition (EMT) is a crucial process in cancer progression and metastasis. Study of metabolic changes during the EMT process is important in seeking to understand the biochemical changes...