L M Houdebine
Overview
Explore the profile of L M Houdebine including associated specialties, affiliations and a list of published articles.
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163
Citations
897
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Recent Articles
1.
Frewer L, Kleter G, Brennan M, Coles D, Fischer A, Houdebine L, et al.
N Biotechnol
. 2013 Apr;
30(5):447-60.
PMID: 23567982
The interdisciplinary EC consortium (the PEGASUS project) aimed to examine the issues raised by the development, implementation and commercialisation of genetically modified (GM) animals, and derivative foods and pharmaceutical products....
2.
Jolivet G, Daniel-Carlier N, Thepot D, Rival-Gervier S, Houdebine L
Animal
. 2012 Mar;
2(3):336-43.
PMID: 22445034
Milk protein genes are among the most intensively expressed and they are active only in epithelial mammary cells of lactating animals. They code for proteins which represent 30% of the...
3.
Houdebine L, Renard J
Rev Sci Tech
. 2005 Aug;
24(1):265-74.
PMID: 16110894
Reproduction by cloning can eliminate some of the problems inherent to sexual reproduction, but it creates others. The genetic heritage of nucleus donor cells and the genetic status of clones...
4.
Malassagne B, Regimbeau J, Taboit F, Troalen F, Chereau C, Moire N, et al.
Xenotransplantation
. 2003 Apr;
10(3):267-77.
PMID: 12694547
Background: Hyperacute rejection (HAR) of discordant xenografts in the pig-to-human combination can be prevented using tranplants expressing transgenic molecules that inhibit human complement. Hypodermin A (HA), a serine esterase that...
5.
Jolivet G, Meusnier C, Chaumaz G, Houdebine L
J Cell Biochem
. 2001 Aug;
82(3):371-86.
PMID: 11500914
Previous studies have shown that both the signal transducer and activator of transcription 5 (STAT5) and the CCAAT enhancer binding proteins (C/EBPs) are involved in the regulation of casein gene...
6.
Galet C, Le Bourhis C, Chopineau M, Le Griec G, PERRIN A, Magallon T, et al.
Mol Cell Endocrinol
. 2001 Apr;
174(1-2):31-40.
PMID: 11306169
Equine chorionic gonadotropin (eCG) is a heavily glycosylated glycoprotein composed of non-covalently linked alpha- and beta-subunits. eCG possesses the particularity to bind to both LH and FSH receptors in species...
7.
Houdebine L
Transgenic Res
. 2000 Dec;
9(4-5):305-20.
PMID: 11131009
The production of recombinant proteins is one of the major successes of biotechnology. Animal cells are required to synthesize proteins with the appropriate post-translational modifications. Transgenic animals are being used...
8.
Attal J, Theron M, Puissant C, Houdebine L
Gene Expr
. 2000 Aug;
8(5-6):299-309.
PMID: 10947079
Specific structures found in the mRNA of picornavirus are known to allow a cap-independent translation. These structures, named internal ribosome entry sites (IRES), are also able to favor translation of...
9.
Attal J, Theron M, Rival S, Puissant C, Houdebine L
Mol Biol Rep
. 2000 Aug;
27(1):21-6.
PMID: 10939522
The IRES from poliovirus and from encephalomyocarditis virus (EMCV) added between the cap and the AUG initiator codon were strong inhibitors of chloramphenicol acetyltransferase gene expression in three different cell...
10.
Houdebine L
Pathol Biol (Paris)
. 2000 Jun;
48(4):383-6.
PMID: 10868403
Transgenesis can theoretically add a foreign gene or specifically replace an endogenous gene by another gene. Gene addition in mammals is generally achieved by DNA microinjection into one-cell embryos. Gene...