L L Brennan
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Explore the profile of L L Brennan including associated specialties, affiliations and a list of published articles.
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4
Citations
153
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Recent Articles
1.
Guinan E, Cole G, Wylie W, Kelner R, Janec K, Yuan H, et al.
Am J Transplant
. 2016 Jan;
16(7):2187-95.
PMID: 26790369
Short-term outcomes of kidney transplantation have improved dramatically, but chronic rejection and regimen-related toxicity continue to compromise overall patient outcomes. Development of regulatory T cells (Tregs) as a means to...
2.
Barbon C, Davies J, Voskertchian A, Kelner R, Brennan L, Nadler L, et al.
Am J Transplant
. 2014 Jan;
14(2):305-18.
PMID: 24410845
Allostimulation with concurrent costimulatory blockade induces alloantigen-specific hyporesponsiveness in responder T cells ("alloanergization"). Alloanergized responder cells also acquire alloantigen-specific suppressive activity, suggesting this strategy induces active immune tolerance. While this...
3.
Guinan E, Boussiotis V, Neuberg D, Brennan L, Hirano N, Nadler L, et al.
N Engl J Med
. 1999 Jun;
340(22):1704-14.
PMID: 10352162
Background: Successful allogeneic bone marrow transplantation relies on global immunosuppression or elimination of T cells. In contrast, the induction of anergy can inactivate specific sets of alloreactive T cells in...
4.
Parsons S, Neault M, Lehmann L, Brennan L, Eickhoff C, Kretschmar C, et al.
Bone Marrow Transplant
. 1998 Nov;
22(7):669-74.
PMID: 9818694
Children with neuroblastoma receiving high-dose carboplatin as part of their conditioning regimen for autologous marrow transplantation have a high incidence of speech frequency hearing loss. We evaluated hearing loss in...