L Kjer-Nielsen
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Explore the profile of L Kjer-Nielsen including associated specialties, affiliations and a list of published articles.
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12
Citations
206
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Recent Articles
1.
Kostenko L, Kjer-Nielsen L, Nicholson I, Hudson F, Lucas A, Foley B, et al.
Tissue Antigens
. 2011 Apr;
78(1):11-20.
PMID: 21501118
HLA-B57 and HLA-B58 are major histocompatibility class (MHC)-I allotypes that are potentially predictive of important clinical immune phenotypes. HLA-B*5701 is strongly associated with hypersensitivity to the HIV drug abacavir, liver...
2.
Chang L, Kjer-Nielsen L, Flynn S, Brooks A, Mannering S, Honeyman M, et al.
Tissue Antigens
. 2003 Nov;
62(5):408-17.
PMID: 14617048
We describe a strategy for identifying ligands of human leukocyte antigen (HLA) class I molecules based on a peptide library-mediated in vitro assembly of recombinant class I molecules. We established...
3.
Brown D, Heimann K, Lock J, Kjer-Nielsen L, van Vliet C, Stow J, et al.
Traffic
. 2001 May;
2(5):336-44.
PMID: 11350629
Vesicular carriers for intracellular transport associate with unique sets of accessory molecules that dictate budding and docking on specific membrane domains. Although many of these accessory molecules are peripheral membrane...
4.
Kjer-Nielsen L, van Vliet C, Erlich R, Toh B, Gleeson P
J Cell Sci
. 1999 May;
112 ( Pt 11):1645-54.
PMID: 10318758
Vesicle transport requires the recruitment of cytosolic proteins to specific membrane compartments. We have previously characterised a brefeldin A-sensitive trans-Golgi network-localised protein (p230) that is associated with a population of...
5.
Kjer-Nielsen L, Teasdale R, van Vliet C, Gleeson P
Curr Biol
. 1999 Apr;
9(7):385-8.
PMID: 10209125
The mechanism by which peripheral membrane proteins are targeted to the cytoplasmic face of the Golgi apparatus is poorly understood. Previously, we have identified a carboxy-terminal domain of the trans-Golgi-network...
6.
Heath W, Kjer-Nielsen L, Hoffmann M
J Immunol
. 1993 Dec;
151(11):5993-6001.
PMID: 8245444
To examine the influence of avidity on the helper dependence of CD8+ T cells, purified CD8+ T cells from transgenic mice expressing a TCR specific for H-2Kb were tested for...
7.
Kjer-Nielsen L, Holmberg K, Perera J, McCluskey J
Transgenic Res
. 1992 Jul;
1(4):182-7.
PMID: 1301211
Plasmid vector sequences were retained (vector+), or removed (vector-) from hybrid major histocompatibility complex gene constructs prior to microinjection of fertilized ova for the production of transgenic mice. In transgenic...
8.
Brooks A, Hartley S, Kjer-Nielsen L, Perera J, Goodnow C, Basten A, et al.
Proc Natl Acad Sci U S A
. 1991 Apr;
88(8):3290-4.
PMID: 1707537
An in vitro model was used to investigate the potential for different structural forms of endogenous antigen to be processed and presented by major histocompatibility complex class II molecules. For...
9.
Slattery R, Kjer-Nielsen L, Allison J, Charlton B, Mandel T, Miller J
Nature
. 1990 Jun;
345(6277):724-6.
PMID: 1972779
The non-obese diabetic (NOD) mouse develops insulin-dependent diabetes mellitus (IDDM) with mononuclear cell infiltration of the islets of Langerhans and selective destruction of the insulin-producing beta-cells, as in humans. Most...
10.
Kjer-Nielsen L, Perera J, Boyd L, Margulies D, McCluskey J
J Immunol
. 1990 Apr;
144(8):2915-24.
PMID: 1969876
We have evaluated the relative contributions of the extracellular and cytoplasmic domains of MHC class II molecules in determining the Ag-processing requirements for class II-restricted Ag presentation to T cells....