L K Lane
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Explore the profile of L K Lane including associated specialties, affiliations and a list of published articles.
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Citations
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Recent Articles
1.
Blostein R, Daly S, Boxenbaum N, Lane L, Arguello J, Lingrel J, et al.
Acta Physiol Scand Suppl
. 1998 Oct;
643:275-81.
PMID: 9789570
This paper summarizes experiments concerned with the functional consequences of mutations in cytoplasmic regions of the alpha 1 subunit of the Na,K-ATPase, in particular the amino terminus, the first cytoplasmic...
2.
Boxenbaum N, Daly S, Javaid Z, Lane L, Blostein R
J Biol Chem
. 1998 Aug;
273(36):23086-92.
PMID: 9722535
Mutations comprising either deletion of 32 amino acids from the NH2 terminus (alpha1M32) or a Glu233 --> Lys substitution in the first M2-M3 cytoplasmic loop (E233K) of the alpha1-subunit of...
3.
Nestor N, Lane L, Blostein R
Ann N Y Acad Sci
. 1997 Dec;
834:579-81.
PMID: 9405867
No abstract available.
4.
Daly S, Lane L, Blostein R
Ann N Y Acad Sci
. 1997 Dec;
834:489-97.
PMID: 9405851
No abstract available.
5.
Daly S, Blostein R, Lane L
J Biol Chem
. 1997 Mar;
272(10):6341-7.
PMID: 9045654
During kinetic studies of mutant rat Na,K-ATPases, we identified a spontaneous mutation in the first cytoplasmic loop between transmembrane helices 2 and 3 (H2-H3 loop) which results in a functional...
6.
Daly S, Lane L, Blostein R
J Biol Chem
. 1996 Sep;
271(39):23683-9.
PMID: 8798590
The alpha2 isoform of the Na,K-ATPase exhibits kinetic behavior distinct from that of the alpha1 isoform. The distinctive behavior is apparent when the reaction is carried out under conditions (micromolar...
7.
Daly S, Lane L, Blostein R
J Biol Chem
. 1994 Sep;
269(39):23944-8.
PMID: 7929042
One region of marked sequence diversity among the highly homologous alpha isoforms of the Na,K-ATPase is the lysine-rich NH2 terminus. Expression of a mutant cDNA encoding an alpha 1 protein,...
8.
Charlemagne D, Orlowski J, Oliviero P, Rannou F, Sainte Beuve C, Swynghedauw B, et al.
J Biol Chem
. 1994 Jan;
269(2):1541-7.
PMID: 8288620
To determine if an altered expression of the Na,K-ATPase alpha isoform genes is responsible for an observed increase in cardiac glycoside sensitivity in compensatory hypertrophy, we performed Northern and slot...
9.
Lane L
Biochem Mol Biol Int
. 1993 Dec;
31(5):817-22.
PMID: 8136699
Site-specific mutagenesis was used to prepare the following substitutions of the rat alpha 1 Na,K-ATPase: Cys 513-->Ala, Cys 454+458+459-->Ala and Cys 551-->Ser. Ouabain-resistant HeLa cell cells expressing rat alpha 1...
10.
Lane L, Feldmann J, Flarsheim C, Rybczynski C
J Biol Chem
. 1993 Aug;
268(24):17930-4.
PMID: 8394354
Previous chemical modification studies have suggested that Cys-369, Cys-658, Lys-482, Asp-712, and Asp-716 are essential for Na,K-ATPase function. To determine if the side chains of these amino acid residues are...