L Jean Patterson
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Explore the profile of L Jean Patterson including associated specialties, affiliations and a list of published articles.
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28
Citations
1059
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Recent Articles
1.
Deschamps A, DeRocco A, Bok K, Patterson L
J Infect Dis
. 2023 Oct;
228(Suppl 6):S355-S358.
PMID: 37849398
Given the increased risk of pandemics driven by emerging and reemerging infectious diseases, it is imperative that the United States and global scientific community be better prepared for future threats...
2.
Cassetti M, Pierson T, Patterson L, Bok K, DeRocco A, Deschamps A, et al.
J Infect Dis
. 2022 Jul;
227(12):1433-1441.
PMID: 35876700
Severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1) emerged 20 years ago, presaging a series of subsequent infectious disease epidemics of international concern. The recent emergence of SARS-CoV-2 has underscored the...
3.
Valentin A, McKinnon K, Li J, Rosati M, Kulkarni V, Pilkington G, et al.
Clin Immunol
. 2014 Sep;
155(1):91-107.
PMID: 25229164
To identify the most promising vaccine candidates for combinatorial strategies, we compared five SIV vaccine platforms including recombinant canary pox virus ALVAC, replication-competent adenovirus type 5 host range mutant RepAd,...
4.
Vargas-Inchaustegui D, Tuero I, Mohanram V, Musich T, Pegu P, Valentin A, et al.
Clin Immunol
. 2014 Jun;
153(2):308-22.
PMID: 24907411
Combinatorial HIV/SIV vaccine approaches targeting multiple arms of the immune system might improve protective efficacy. We compared SIV-specific humoral immunity induced in rhesus macaques by five vaccine regimens. Systemic regimens...
5.
Vaccari M, Halwani R, Patterson L, Boasso A, Beal J, Tryniszewska E, et al.
J Virol
. 2013 Jan;
87(6):3526-37.
PMID: 23325679
We compared the relative efficacies against simian immunodeficiency virus (SIV) challenge of three vaccine regimens that elicited similar frequencies of SIV-specific CD4(+) and CD8(+) T-cell responses but differed in the...
6.
Vargas-Inchaustegui D, Xiao P, Tuero I, Patterson L, Robert-Guroff M
J Immunol
. 2012 Jul;
189(4):1878-85.
PMID: 22798665
Control of infectious disease may be accomplished by successful vaccination or by complex immunologic and genetic factors favoring Ag-specific multicellular immune responses. Using a rhesus macaque model, we evaluated Ag-specific...
7.
Patterson L, Kuate S, Daltabuit-Test M, Li Q, Xiao P, McKinnon K, et al.
Clin Vaccine Immunol
. 2012 Mar;
19(5):629-37.
PMID: 22441384
Although priming with replicating adenovirus type 5 host range mutant (Ad5hr)-human immunodeficiency virus (HIV)/simian immunodeficiency virus (SIV) recombinants, followed by HIV/SIV envelope boosting, has proven highly immunogenic, resulting in protection...
8.
Xiao P, Patterson L, Kuate S, Brocca-Cofano E, Thomas M, Venzon D, et al.
J Virol
. 2012 Feb;
86(8):4644-57.
PMID: 22345466
We have shown that sequential replicating adenovirus type 5 host range mutant human immunodeficiency virus/simian immunodeficiency virus (HIV/SIV) recombinant priming delivered first intranasally (i.n.) plus orally and then intratracheally (i.t.),...
9.
Demberg T, Ettinger A, Aladi S, McKinnon K, Kuddo T, Venzon D, et al.
Vaccine
. 2011 Jun;
29(35):6017-28.
PMID: 21708207
It has been proposed that microbial translocation might play a role in chronic immune activation during HIV/SIV infection. Key roles in fighting bacterial and fungal infections have been attributed to...
10.
Brocca-Cofano E, McKinnon K, Demberg T, Venzon D, Hidajat R, Xiao P, et al.
Vaccine
. 2011 Mar;
29(17):3310-9.
PMID: 21382487
An effective HIV vaccine requires strong systemic and mucosal, cellular and humoral immunity. Numerous non-human primate studies have investigated memory T cells, but not memory B cells. Humoral immunologic memory...