L J van Keulen
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Explore the profile of L J van Keulen including associated specialties, affiliations and a list of published articles.
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12
Citations
299
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Recent Articles
1.
van Keulen L, Schreuder B, Vromans M, Langeveld J, Smits M
Arch Virol Suppl
. 2001 Feb;
(16):57-71.
PMID: 11214935
Although scrapie has been known for a long time as a natural disease of sheep and goats, the pathogenesis in its natural host still remains unclear. To study the pathogenesis...
2.
van Keulen L, Langeveld J, Garssen G, Jacobs J, Schreuder B, Smits M
Vet Q
. 2000 Nov;
22(4):197-200.
PMID: 11087129
Cows affected with bovine spongiform encephalopathy (BSE) display chronic neurological signs consisting of behavioural changes, abnormalities of posture and movement, and/or hyperaesthesia. At present, there are no laboratory test available...
3.
van der Poel W, Van der Heide R, van Amerongen G, van Keulen L, Wellenberg G, Bourhy H, et al.
Arch Virol
. 2000 Oct;
145(9):1919-31.
PMID: 11043951
In July 1997 a lyssavirus was isolated in Denmark from a colony of Egyptian flying foxes (Rousettus aegyptiacus) originating from a Dutch zoo. Sequencing of a 400 nucleotides coding region...
4.
Garssen G, van Keulen L, Farquhar C, Smits M, Jacobs J, Bossers A, et al.
Microsc Res Tech
. 2000 Jun;
50(1):32-9.
PMID: 10871546
Three rabbit antibodies (R521, R505, R524) were produced, and raised to synthetic peptides corresponding to residues 94-105, 100-111, and 223-234, respectively, of the sheep prion protein (PrP). Epitope mapping analysis...
5.
van Keulen L, Schreuder B, Vromans M, Langeveld J, Smits M
J Comp Pathol
. 1999 Jun;
121(1):55-63.
PMID: 10373293
The scrapie-associated prion protein (PrPSc), which is closely associated with scrapie infectivity, accumulates in the brain and lymphoid tissues of sheep with natural scrapie. The most probable portal of entry...
6.
Schreuder B, van Keulen L, Vromans M, Langeveld J, Smits M
Vet Rec
. 1998 Jun;
142(21):564-8.
PMID: 9634704
Preliminary findings have indicated that in naturally infected sheep, fully susceptible to scrapie (VRQ-homozygous), PrPSc can be detected in the tonsils approximately one year before the expected onset of clinical...
7.
Schreuder B, Geertsma R, van Keulen L, van Asten J, Enthoven P, Oberthur R, et al.
Vet Rec
. 1998 Jun;
142(18):474-80.
PMID: 9612912
The efficacy of the procedures in use at the two rendering plants in the Netherlands was assessed on a laboratory-scale using procedures that simulated the pressure cooking part of the...
8.
Schreuder B, van Keulen L, Smits M, Langeveld J, Stegeman J
Vet Q
. 1997 Nov;
19(3):105-13.
PMID: 9323850
After a brief description of the scrapie situation in the Netherlands, the technical progress made in aspects of scrapie diagnosis is reported. Emphasis is placed on the use of immuno-histochemistry...
9.
van Keulen L, Wesdorp J, Kooistra H
Vet Pathol
. 1996 Jul;
33(4):451-3.
PMID: 8817849
A 9-year-old male Doberman Pinscher was referred to the Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, for polyuria/polydipsia, anorexia, and vomiting. Laboratory examination of...
10.
Schreuder B, van Keulen L, Vromans M, Langeveld J, Smits M
Nature
. 1996 Jun;
381(6583):563.
PMID: 8637589
No abstract available.