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L J Bugaj

Explore the profile of L J Bugaj including associated specialties, affiliations and a list of published articles. Areas
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Articles 2
Citations 129
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Recent Articles
1.
Bugaj L, Sabnis A, Mitchell A, Garbarino J, Toettcher J, Bivona T, et al.
Science . 2018 Sep; 361(6405). PMID: 30166458
The Ras-Erk (extracellular signal-regulated kinase) pathway encodes information in its dynamics; the duration and frequency of Erk activity can specify distinct cell fates. To enable dynamic encoding, temporal information must...
2.
Bugaj L, Spelke D, Mesuda C, Varedi M, Kane R, Schaffer D
Nat Commun . 2015 Apr; 6:6898. PMID: 25902152
Transmembrane receptors are the predominant conduit through which cells sense and transduce extracellular information into intracellular biochemical signals. Current methods to control and study receptor function, however, suffer from poor...