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L J A Stalpers

Explore the profile of L J A Stalpers including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 714
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Recent Articles
1.
Adam J, Poel E, van Eck Smit B, Mom C, Stalpers L, Laan J, et al.
BMC Cancer . 2024 Apr; 24(1):513. PMID: 38654241
Background: [F]FDG-PET/CT is used for staging and treatment planning in patients with locally advanced cervical cancer (LACC). We studied if a PET-based prediction model could provide additional risk stratification beyond...
2.
Oei A, Kok H, Oei S, Horsman M, Stalpers L, Franken N, et al.
Adv Drug Deliv Rev . 2020 Jan; 163-164:84-97. PMID: 31982475
Mild hyperthermia, local heating of the tumour up to temperatures <43 °C, has been clinically applied for almost four decades and has been proven to substantially enhance the effectiveness of...
3.
Visser J, de Boer P, Crama K, van Kesteren Z, Rasch C, Stalpers L, et al.
Radiat Oncol . 2019 Jul; 14(1):126. PMID: 31300000
Background: Online magnetic resonance imaging (MRI)-guided radiotherapy of cervical cancer has the potential to further reduce dose to organs at risk (OAR) as compared to a library of plans (LOP)...
4.
Kok H, Schooneveldt G, Bakker A, de Kroon-Oldenhof R, Korshuize-van Straten L, de Jong C, et al.
Int J Hyperthermia . 2018 Oct; 35(1):330-339. PMID: 30300028
Introduction: On-line adaptive hyperthermia treatment planning can be useful to suppress treatment limiting hot spots and improve tumor temperatures during locoregional hyperthermia. This requires adequate prediction of changes in heating...
5.
van Leeuwen C, Oei A, Crezee J, Bel A, Franken N, Stalpers L, et al.
Radiat Oncol . 2018 May; 13(1):96. PMID: 29769103
Background: Prediction of radiobiological response is a major challenge in radiotherapy. Of several radiobiological models, the linear-quadratic (LQ) model has been best validated by experimental and clinical data. Clinically, the...
6.
van Leeuwen C, Crezee J, Oei A, Franken N, Stalpers L, Bel A, et al.
Int J Hyperthermia . 2018 May; 34(7):901-909. PMID: 29749270
Purpose: Thermoradiotherapy is an effective treatment for locally advanced cervical cancer. However, the optimal time interval between radiotherapy and hyperthermia, resulting in the highest therapeutic gain, remains unclear. This study...
7.
Kok H, Korshuize-van Straten L, Bakker A, de Kroon-Oldenhof R, Westerveld G, Versteijne E, et al.
Int J Hyperthermia . 2017 Nov; 34(7):1082-1091. PMID: 29145750
Background: The effectiveness of hyperthermia is strongly dependent on the achieved tumour temperatures. Phased-array systems allow flexible power steering to realise good tumour heating while avoiding excessive heating in normal...
8.
Laan J, van Lonkhuijzen L, van Os R, Tytgat K, Fajardo R, Pieters B, et al.
Gynecol Oncol . 2017 Oct; 147(3):684-689. PMID: 29074259
Objective: To evaluate the frequency of and risk factors for severe late bowel toxicity after curative radiotherapy in women treated for locally advanced cervical cancer. Methods: Included were 515 women...
9.
van Leeuwen C, Oei A, Ten Cate R, Franken N, Bel A, Stalpers L, et al.
Int J Hyperthermia . 2017 May; 34(1):30-38. PMID: 28540813
Purpose: Biological modelling of thermoradiotherapy may further improve patient selection and treatment plan optimisation, but requires a model that describes the biological effect as a function of variables that affect...
10.
van Leeuwen C, Crezee J, Oei A, Franken N, Stalpers L, Bel A, et al.
Int J Hyperthermia . 2016 Oct; 33(2):160-169. PMID: 27744728
Purpose: Currently, clinical decisions regarding thermoradiotherapy treatments are based on clinical experience. Quantification of the radiosensitising effect of hyperthermia allows comparison of different treatment strategies, and can support clinical decision-making...