L Hieber
Overview
Explore the profile of L Hieber including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
181
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Recent Articles
1.
Scherthan H, Hieber L, Braselmann H, Meineke V, Zitzelsberger H
Biochem Biophys Res Commun
. 2008 May;
371(4):694-7.
PMID: 18457664
DNA double strand breaks (DSBs) pose a severe hazard to the genome as erroneous rejoining of DSBs can lead to mutation and cancer. Here, we have investigated the correlation between...
2.
Unger K, Zurnadzhy L, Walch A, Mall M, Bogdanova T, Braselmann H, et al.
Br J Cancer
. 2006 Apr;
94(10):1472-7.
PMID: 16641909
Tissue samples from 13 post-Chernobyl childhood thyroid tumours that occurred within a short period of time (4-8 years) after the Chernobyl accident have been investigated by interphase FISH analysis for...
3.
Lohrer H, Hieber L, Zitzelsberger H
Carcinogenesis
. 2002 Oct;
23(10):1577-82.
PMID: 12376464
Lack of a chromatin structure and histone protection makes mitochondrial DNA susceptible to oxidative damage. Suboptimal DNA repair leads to a higher frequency of mitochondrial mutations, which are associated with...
4.
Lohrer H, Braselmann H, Richter H, Jackl G, Herbeck J, Hieber L, et al.
Int J Radiat Biol
. 2001 Sep;
77(8):891-9.
PMID: 11571023
Purpose: To determine the instability of microsatellite sequences in post-Chernobyl thyroid tumours from children and young adults, and to ascertain whether they correlated with the age of the patient at...
5.
Zitzelsberger H, Bruch J, Smida J, Hieber L, Peddie C, Bryant P, et al.
Int J Cancer
. 2001 Jun;
96(3):166-77.
PMID: 11410885
In vitro model cell systems are important tools for studying mechanisms of radiation-induced neoplastic transformation of human epithelial cells. In our study, the human thyroid epithelial cell line HTori-3 was...
6.
Riches A, Peddie C, Rendell S, Bryant P, Zitzelsberger H, Bruch J, et al.
Radiat Res
. 2000 Dec;
155(1 Pt 2):222-229.
PMID: 11121238
Neoplastic transformation of human epithelial cells by radiation has previously been investigated using cell lines immortalized with viral vectors. There are disadvantages to this approach, and we report here the...
7.
Richter H, Lohrer H, Hieber L, Kellerer A, Lengfelder E, BAUCHINGER M
Carcinogenesis
. 1999 Dec;
20(12):2247-52.
PMID: 10590215
DNA from 129 paired thyroid tumorous and non-tumorous tissue samples of Belarussian children (102 patients; age at surgery </=18 years) and adults (27 patients; age at surgery 19-35 years), who...
8.
Smida J, Salassidis K, Hieber L, Zitzelsberger H, Kellerer A, Demidchik E, et al.
Int J Cancer
. 1999 Feb;
80(1):32-8.
PMID: 9935226
Rearrangements of the ret oncogene were investigated in papillary thyroid carcinomas (PTC) from 51 Belarussian children with a mean age of 3 years at the time of the Chernobyl radiation...
9.
Zitzelsberger H, Lehmann L, Hieber L, Weier H, Janish C, Fung J, et al.
Cancer Res
. 1999 Jan;
59(1):135-40.
PMID: 9892198
Thyroid carcinoma incidence is increased significantly after ionizing irradiation; however, the possible mechanisms have not yet been identified. To provide clues for an understanding of the radiation-induced transformation of thyroid...
10.
Mill A, Frankenberg D, Bettega D, Hieber L, Saran A, Allen L, et al.
J Radiol Prot
. 1998 Jul;
18(2):79-100.
PMID: 9656189
For the assessment of radiation risk at low doses, it is presumed that the shape of the low-dose-response curve in humans for cancer induction is linear. Epidemiological data alone are...