L H J Looijenga
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Explore the profile of L H J Looijenga including associated specialties, affiliations and a list of published articles.
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49
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1203
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Recent Articles
1.
van der Wilk B, Eyck B, Doukas M, Spaander M, Schoon E, Krishnadath K, et al.
Br J Surg
. 2020 Aug;
107(13):1791-1800.
PMID: 32757307
Background: Active surveillance has been proposed for patients with oesophageal cancer in whom there is a complete clinical response after neoadjuvant chemoradiotherapy (nCRT). However, endoscopic biopsies have limited negative predictive...
2.
Camacho-Moll M, Macdonald J, Looijenga L, Rimmer M, Donat R, Marwick J, et al.
BMC Cancer
. 2019 Nov;
19(1):1124.
PMID: 31744479
Background: Testicular germ cell cancer (TGCC) develops from pre-malignant germ neoplasia in situ (GCNIS) cells. GCNIS originates from fetal gonocytes (POU5F1/MAGE-A4), which fail to differentiate to pre-spermatogonia (POU5F1/MAGE-A4) and undergo...
3.
Boellaard W, Gillis A, van Leenders G, Stoop H, van Agthoven T, Dorssers L, et al.
Andrology
. 2019 Feb;
7(4):463-468.
PMID: 30786164
Background: The microRNA-371a-3p (miR-371a-3p) has been reported to be an informative liquid biopsy (serum and plasma) molecular biomarker for both diagnosis and follow-up of patients with a malignant (testicular) germ...
4.
Cools M, Wolffenbuttel K, Hersmus R, Mendonca B, Kaprova J, Drop S, et al.
Hum Reprod
. 2017 Nov;
32(12):2561-2573.
PMID: 29121256
Study Question: What is the prevalence of malignant testicular germ cell tumors (TGCT) and its precursors, (pre-) germ cell neoplasia in situ (GCNIS), in late teenagers and adults who have...
5.
Andreescu C, Alwani R, Hofland J, Looijenga L, de Herder W, Hofland L, et al.
Eur J Endocrinol
. 2017 Aug;
177(5):K13-K20.
PMID: 28819015
Cushing syndrome (CS) during pregnancy is a rare condition with only a few cases reported in the literature. Misdiagnosis of CS is common because of overlapping features like fatigue, weight...
6.
Ten Kate F, van Olphen S, Bruno M, Wijnhoven B, van Lanschot J, Looijenga L, et al.
Br J Surg
. 2017 Jul;
104(10):1327-1337.
PMID: 28692180
Background: Oesophageal adenocarcinoma (OAC) is a highly aggressive malignancy with poor survival, which is highly variable amongst patients with comparable conventional prognosticators. Therefore molecular biomarkers are urgently needed to improve...
7.
Wolffenbuttel K, Hersmus R, Stoop H, Biermann K, Hoebeke P, Cools M, et al.
J Pediatr Urol
. 2016 Oct;
12(6):411-416.
PMID: 27769830
Recent studies on gonadal histology have improved the understanding of germ cell malignancy risk in patients with disorders of sex development (DSD), and evidence-based gonadal management strategies are gradually emerging....
8.
Oosterhuis J, Stoop J, Rijlaarsdam M, Biermann K, Smit V, Hersmus R, et al.
Andrology
. 2014 Nov;
3(1):70-7.
PMID: 25427839
Four cases are reported meeting the criteria of a pediatric (i.e., Type I) testicular germ cell tumor (TGCT), apart from the age of presentation, which is beyond childhood. The tumors...
9.
Rijlaarsdam M, van Agthoven T, Gillis A, Patel S, Hayashibara K, Lee K, et al.
Andrology
. 2014 Nov;
3(1):85-91.
PMID: 25382245
microRNAs (miRs) are short non-coding RNA molecules (≈21 nucleotides) involved in regulation of translation. As such they are crucial for normal cell development and differentiation as well as cellular maintenance....
10.
Bakker N, Wolffenbuttel K, Looijenga L, Hokken-Koelega A
J Urol
. 2014 Aug;
193(1):291-8.
PMID: 25109686
Purpose: Boys with Prader-Willi syndrome often have undescended testes. Prospective studies on the treatment of cryptorchidism in these patients are lacking. We evaluated the effects of human chorionic gonadotropin administration...