L G WHITE
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Explore the profile of L G WHITE including associated specialties, affiliations and a list of published articles.
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20
Citations
51
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Recent Articles
1.
Shrewsbury R, Oliver S, WHITE L
Artif Cells Blood Substit Immobil Biotechnol
. 1994 Jan;
22(4):1237-42.
PMID: 7849928
Desmethylimipramine (desipramine, DMI) is predominantly 2-hydroxylated to 2-hydroxydesipramine, and the remainder is N-demethylated to didesmethylimipramine (DDMI) in both rats and man. DMI 2-hydroxylation is mediated by the same cytochrome P-450...
2.
Shrewsbury R, Hong D, WHITE L, Gordon T
J Pharm Pharmacol
. 1992 Feb;
44(2):84-8.
PMID: 1378493
The effects of Fluosol-DA (Fluosol) and Hespan haemodilution on the nonmicrosomal acetylation of sulphadimidine were studied in male rats. Fluosol increased the acetylsulphadimidine percent excreted in urine, the metabolic formation...
3.
Shrewsbury R, WHITE L
J Pharm Pharmacol
. 1990 Nov;
42(11):813-6.
PMID: 1982312
Antipyrine disposition has been determined in the rat following administration of Fluosol-DA by an intravenous infusion without blood removal or a haemodilution procedure, and compared with data from sham haemodiluted...
4.
Shrewsbury R, WHITE L
J Pharm Pharmacol
. 1990 Jul;
42(7):511-2.
PMID: 1980296
The effect of moderate Fluosol-DA haemodilution on intestinal blood flow has been investigated in the rat. Antipyrine in-situ intestinal absorption is blood flow limited, and did not alter 0.5, 24,...
5.
Shrewsbury R, WHITE L
Res Commun Chem Pathol Pharmacol
. 1990 Mar;
67(3):411-4.
PMID: 2343186
Two reports of antipyrine disposition in rats after hemodilution with 20, 40, or 80 ml/kg of Fluosol-DA are evaluated to determine if the extent of hemodilution influenced cytochrome P-450 mediated...
6.
Shrewsbury R, WHITE L
Experientia
. 1990 Feb;
46(2):213-7.
PMID: 2303130
Hemodilution with 40 ml/kg of Fluosol or saline reduced the acetaminophen Vd and the acetaminophen sulfate ClM at 48 or 72 h, respectively. Fluosol hemodilution increased the acetaminophen renal excretion...
7.
Shrewsbury R, Oliver S, Lewis L, Anderson W, WHITE L
J Pharm Pharmacol
. 1989 Aug;
41(8):582-4.
PMID: 2571710
Phenytoin kinetics were determined in rats in which the blood was moderately haemodiluted with 20 or 40 mL kg-1 of Fluosol-DA or normal saline. Rats received one of three intravenous...
8.
Shrewsbury R, WHITE L
Res Commun Chem Pathol Pharmacol
. 1989 Jun;
64(3):455-62.
PMID: 2781142
Antipyrine metabolism was determined after hemodilution with 40 ml/kg of Fluosol in conscious, unrestrained female and male rats. Rats received an intravenous antipyrine dose (20 mg/kg) 24, 48, or 72...
9.
10.
Shrewsbury R, Oliver S, WHITE L
Biomater Artif Cells Artif Organs
. 1989 Jan;
17(4):393-402.
PMID: 2605353
Antipyrine metabolism was determined in conscious, unrestrained rats after isovolemic hemodilution with FluosolR-DA. Rats received an intravenous antipyrine dose (20 mg/kg) 0.5, 24, 48, or 72 hours after hemodilution and...