L G Lum
Overview
Explore the profile of L G Lum including associated specialties, affiliations and a list of published articles.
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99
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789
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Recent Articles
11.
Activated T-cell and bispecific antibody immunotherapy for high-risk breast cancer. Bench to bedside
Lum L, Sen M
Acta Haematol
. 2001 Jul;
105(3):130-6.
PMID: 11463985
Nontoxic approaches are needed to improve overall survival (OS) and progression-free survival (PFS) for high-risk breast cancer. Combination immunotherapy (IT) consisting of activated T cells (ATC), interleukin-2 (IL-2), and CTL...
12.
Sen M, Wankowski D, Garlie N, Siebenlist R, Van Epps D, LeFever A, et al.
J Hematother Stem Cell Res
. 2001 May;
10(2):247-60.
PMID: 11359672
Relapse after adjuvant chemotherapy or high-dose chemotherapy with stem cell transplant for high-risk breast cancer remains high and new strategies that provide additional antitumor effects are needed. This report describes...
13.
Lum L
CA Cancer J Clin
. 2001 Feb;
49(2):74-100, 65.
PMID: 11198889
The goal of harnessing the immune system to recognize tumor as "nonself" is not new. Now, thanks to new knowledge and new techniques, however, modalities that seek to activate the...
14.
Shibuya T, Wei W, Zormeier M, Ensley J, Sakr W, Mathog R, et al.
Arch Otolaryngol Head Neck Surg
. 2000 Apr;
126(4):473-9.
PMID: 10772300
Objectives: To test whether T-cell CD3 responses are altered in patients with advanced-stage head and neck squamous cell carcinoma (HNSCC) and whether anti-CD3/anti-CD28 (alphaCD3/alphaCD28) bead stimulation could reverse CD3 unresponsiveness....
15.
Shibuya T, Wei W, Zormeier M, Ensley J, Sakr W, Mathog R, et al.
Arch Otolaryngol Head Neck Surg
. 1999 Nov;
125(11):1229-34.
PMID: 10555694
Objective: To test whether anti-CD3/anti-CD28 (alphaCD3/alphaCD28) monoclonal antibodies could be coated on surgical suture and used to enhance T-cell immune function in patients with advanced-stage head and neck squamous cell...
16.
Garlie N, LeFever A, Siebenlist R, Levine B, June C, Lum L
J Immunother
. 1999 Jul;
22(4):336-45.
PMID: 10404435
This report describes the generation of T cells with characteristics that may prove useful for the immunotherapy of cancer. Peripheral blood mononuclear cells obtained from healthy donors were cultured in...
17.
Quinn E, Lum L, Trevor K
Hum Gene Ther
. 1998 Jul;
9(10):1457-67.
PMID: 9681417
Important considerations for T lymphocyte-based gene therapy include efficient gene delivery and expression in primary, human T cells. In this study, retrovirus-mediated gene transfer and the fate of proviral gene...
18.
Shibuya T, Momin F, Abella E, Jacobs J, Karanes C, Ratanatharathorn V, et al.
Otolaryngol Head Neck Surg
. 1995 Dec;
113(6):705-11.
PMID: 7501381
Background: Fever associated with sinus disease in the immunocompromised bone marrow transplant recipient requires prompt evaluation and therapy. Very little is known about the incidence, risk factors, and sequelae of...
19.
Jin N, Lum L, Ratanatharathorn V, SENSENBRENNER L
Exp Hematol
. 1995 Dec;
23(13):1331-6.
PMID: 7498359
Although cytokines produced by activated T cells may accelerate immunohematopoietic reconstitution after autologous bone marrow transplantation (ABMT), there is no direct evidence that infusion of anti-CD3 mAb-activated T cells can...
20.
Jin N, Lum L, Buren E, Lerman S, Walker A, June C
Bone Marrow Transplant
. 1995 Jul;
16(1):103-9.
PMID: 7581108
We previously found that intracellular ionized calcium ([Ca2+]i) flux responses after anti-CD3 crosslinking of CD3/TCR on T cells from allogeneic and autologous bone marrow transplant (BMT) recipients were impaired, Yamagami...