L E Karageorgos
Overview
Explore the profile of L E Karageorgos including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
263
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Recent Articles
1.
Chang M, Karageorgos L, Meikle P
J Biol Regul Homeost Agents
. 2002 Jul;
16(2):147-51.
PMID: 12144129
No abstract available.
2.
ISAAC E, Karageorgos L, Brooks D, Hopwood J, Meikle P
Exp Cell Res
. 2000 Jan;
254(2):204-9.
PMID: 10640418
Lysosomal biogenesis is a complex process requiring the coordinated expression and colocalization of numerous soluble and membrane proteins. In storage disorders, lysosomal biogenesis is regulated at least partially at, or...
3.
Meikle P, Brooks D, Ravenscroft E, Yan M, Williams R, Jaunzems A, et al.
Clin Chem
. 1997 Aug;
43(8 Pt 1):1325-35.
PMID: 9267309
Early diagnosis of lysosomal storage disorders (LSDs), before the onset of irreversible pathologies, will be a key factor in the development of effective therapies for many of these disorders. Newborn...
4.
Karageorgos L, ISAAC E, Brooks D, Ravenscroft E, Davey R, Hopwood J, et al.
Exp Cell Res
. 1997 Jul;
234(1):85-97.
PMID: 9223373
Lysosomal biogenesis is an orchestration of the structural and functional elements of the lysosome to form an integrated organelle and involves the synthesis, targeting, functional residence, and turnover of the...
5.
Karageorgos L, Guo X, Blanch L, Weber B, Anson D, Scott H, et al.
DNA Res
. 1996 Aug;
3(4):269-71.
PMID: 8946167
Sanfilippo A syndrome (MPS-IIIA) is a mucopolysaccharide lysosomal storage disorder caused by a deficiency in the lysosomal enzyme, sulphamidase (EC 3.10.1.1), which is required for the degradation of heparan sulphate....
6.
Stroeher U, Karageorgos L, Brown M, Morona R, Manning P
Gene
. 1995 Dec;
166(1):33-42.
PMID: 8529891
The first four genes (rfbA,B,D,E) of the rfb region of Vibrio cholerae O1 are predicted to encode the enzymes required for the biosynthesis of perosamine, which constitutes the backbone structure...
7.
Morona R, Stroeher U, Karageorgos L, Brown M, Manning P
Gene
. 1995 Dec;
166(1):19-31.
PMID: 8529890
The nucleotide sequence of a region of the rfb genes, encoding biosynthesis of the Vibrio cholerae (Vc) O1 O-antigen, was determined. Analysis of the open reading frames (ORFs) within this...
8.
Stroeher U, Jedani K, Dredge B, Morona R, Brown M, Karageorgos L, et al.
Proc Natl Acad Sci U S A
. 1995 Oct;
92(22):10374-8.
PMID: 7479787
The recent emergence of a pathogenic new non-O1 serotype (O139) of Vibrio cholerae has led to numerous studies in an attempt to identify the origins of this new strain. Our...
9.
Manning P, Stroeher U, Karageorgos L, Morona R
Gene
. 1995 May;
158(1):1-7.
PMID: 7540582
The nucleotide sequence of that part of the Vibrio cholerae (Vc) O1 rfb region encompassing rfbG, rfbH and rfbI is presented. Expression of these genes has enabled the products for...
10.
Stroeher U, Karageorgos L, Morona R, Manning P
Gene
. 1995 Mar;
155(1):67-72.
PMID: 7698669
The rfaD gene of Escherichia coli encodes ADP-L-glycero-D-mannoheptose-6- epimerase, an enzyme required for the biosynthesis of the lipopolysaccharide (LPS) precursor ADP-L-glycero-D- mannoheptose, associated with production of the core oligosaccharide. We...