L E Claes
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Explore the profile of L E Claes including associated specialties, affiliations and a list of published articles.
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57
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1801
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Recent Articles
1.
Claes L, Meyers N
Med Hypotheses
. 2020 Jan;
137:109537.
PMID: 31901879
Sufficient vascularization of the fracture-healing zone is a prerequisite for undisturbed bone healing. One important factor affecting the vascularization is the interfragmentary movement in the fracture-healing zone. Many studies have...
2.
Reich K, Tangl S, Heimel P, Lettner S, Ignatius A, Claes L, et al.
Biomed Res Int
. 2019 Mar;
2019:4250940.
PMID: 30891456
The cyclic axial dynamisation of a stabilised fracture is intended to promote callus formation and bone healing. Most studies focused on biomechanical properties or the quantity of new bone formation....
3.
Epari D, Wehner T, Ignatius A, Schuetz M, Claes L
Med Hypotheses
. 2013 May;
81(2):225-7.
PMID: 23688741
The mechanical conditions in the repair tissues are known to influence the outcome of fracture healing. These mechanical conditions are determined by the stiffness of fixation and limb loading. Experimental...
4.
Reina-Romo E, Gomez-Benito M, Dominguez J, Niemeyer F, Wehner T, Simon U, et al.
J Biomech
. 2010 Dec;
44(5):917-23.
PMID: 21168137
Bone transport is a well accepted technique for the treatment of large bony defects. This process is mechanically driven, where mechanical forces play a central role in the development of...
5.
Claes L
Unfallchirurg
. 2009 Oct;
112(12):1079-81, 1083-4.
PMID: 19844668
The conditions for experimental orthopedic and trauma research in Germany have improved during recent years. At present, however, only a few research centers provide significant and continuous research. Recently advertised...
6.
Chen G, Niemeyer F, Wehner T, Simon U, Schuetz M, Pearcy M, et al.
J Biomech
. 2009 Aug;
42(15):2575-83.
PMID: 19660757
The healing process for bone fractures is sensitive to mechanical stability and blood supply at the fracture site. Most currently available mechanobiological algorithms of bone healing are based solely on...
7.
Claes L, Cunningham J
Clin Orthop Relat Res
. 2009 Feb;
467(8):1964-71.
PMID: 19242768
Fracture healing is normally assessed through an interpretation of radiographs, clinical evaluation, including pain on weight bearing, and a manual assessment of the mobility of the fracture. These assessments are...
8.
Kaspar D, Hedrich C, Schmidt C, Liedert A, Claes L, Ignatius A
Unfallchirurg
. 2005 Sep;
108(1):18, 20-4.
PMID: 16149169
Cell culture studies have shown that NSAID may influence osteogenic activities of osteoblast cultures. However, these studies did not consider long-term effects on differentiating cells. The influence of Voltaren with...
9.
Krischak G, Gebhard F, Mohr W, Krivan V, Ignatius A, Beck A, et al.
Arch Orthop Trauma Surg
. 2004 Jan;
124(2):104-13.
PMID: 14727127
Introduction: Stainless steel and commercially pure titanium are widely used materials in orthopedic implants. However, it is still being controversially discussed whether there are significant differences in tissue reaction and...
10.
Schmidt C, Steinbach G, Decking R, Claes L, Ignatius A
Biomaterials
. 2003 Jul;
24(23):4191-6.
PMID: 12853249
Regarding orthopaedic implant loosening it has been hypothesized that particle-activated macrophages release interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha). This in turn stimulates osteoblasts to release interleukin-6 (IL-6) and prostaglandin...