L D Leserman
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Explore the profile of L D Leserman including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
270
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Recent Articles
1.
Liou H, Polla B, Aragnol D, Leserman L, Griffith I, Glimcher L
Proc Natl Acad Sci U S A
. 1988 Apr;
85(8):2738-42.
PMID: 3258662
Class II major histocompatibility complex molecules are integral membrane glycoproteins whose distribution is limited to certain tissues. To identify the molecular basis for such specificity, the chromatin configuration of the...
2.
Aragnol D, Malissen B, Schiff C, Piron M, Leserman L
J Immunol
. 1986 Nov;
137(10):3347-53.
PMID: 3095429
Different cells and different cell surface determinants of the same cells take up liposomes, bound to them via monoclonal antibodies, with variable efficiency. We have previously reported that T and...
3.
Machy P, Arnold B, Alino S, Leserman L
J Immunol
. 1986 Apr;
136(8):3110-5.
PMID: 2420883
We evaluated the ability of methotrexate-containing liposomes or a ricin alpha-chain immunotoxin, both associated with monoclonal antibodies specific for the major histocompatibility complex-encoded class I molecule H-2Kk, to kill cells...
4.
Aragnol D, Leserman L
Proc Natl Acad Sci U S A
. 1986 Apr;
83(8):2699-703.
PMID: 3458229
In a study designed to evaluate the potential for in vivo manipulation of the circulation and tissue distribution of injected liposomes, mice were passively injected with antidinitrophenyl (anti-DNP) monoclonal antibodies...
5.
Bayard B, Leserman L, Bisbal C, Lebleu B
Eur J Biochem
. 1985 Sep;
151(2):319-25.
PMID: 2992962
Evidence is available for a role of a (2'-5')(A)n-activated endoribonuclease (RNase L) in the antiviral activity of interferon for several RNA viruses. (2'-5')(A)n and their analogues might thus provide an...
6.
Truneh A, Mishal Z, Leserman L
Exp Cell Res
. 1984 Nov;
155(1):50-63.
PMID: 6489465
We have investigated the molecular mechanisms required for endocytosis of MHC-encoded proteins by a cell line, TRH 42, that expresses endogenous murine and introduced human class I molecules. As probes...
7.
Machy P, Leserman L
EMBO J
. 1984 Sep;
3(9):1971-7.
PMID: 6333336
Methotrexate (Mtx) inhibits cellular proliferation by blocking formyl tetrahydrofolate (THF) production. Mtx- or THF-containing liposomes were covalently coupled to Staphylococcus aureus protein A. These liposomes bound specifically in vitro to...
8.
Barbet J, Machy P, Truneh A, Leserman L
Biochim Biophys Acta
. 1984 May;
772(3):347-56.
PMID: 6326829
Leakage of the entrapped anionic fluorophore carboxyfluorescein was used as a measure of the permeability of liposomes to several different acids. Carboxyfluorescein leakage increased with increasing buffer concentration at a...
9.
Weinstein J, Leserman L
Pharmacol Ther
. 1984 Jan;
24(2):207-33.
PMID: 6379684
No abstract available.
10.
Truneh A, Mishal Z, Barbet J, Machy P, Leserman L
Biochem J
. 1983 Jul;
214(1):189-94.
PMID: 6615464
A new technique for the quantification of cellular receptor-mediated endocytosis has been developed based on the analysis by flow cytometry of ligand-bearing liposomes containing the fluorochrome carboxyfluorescein. Carboxyfluorescein encapsulated at...