L Cocault
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Explore the profile of L Cocault including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Levin J, Cocault L, Demerens C, Challier C, Pauchard M, Caen J, et al.
Blood
. 2001 Aug;
98(4):1019-27.
PMID: 11493447
Administration of 5-fluorouracil (5-FU) to mice results in a marked increase in the level of circulating platelets in 10 days. Mice lacking Mpl, the receptor for thrombopoietin (TPO), are thrombocytopenic....
2.
Challier C, Cocault L, Flon M, Pauchard M, Porteu F, Gisselbrecht S, et al.
Oncogene
. 2000 May;
19(16):2033-42.
PMID: 10803464
Mpl is the receptor for thrombopoietin, the primary regulator of platelet production by megakaryocytes. Upon stimulation by its ligand, Mpl receptor induces proliferation and differentiation of hematopoietic cell lines of...
3.
Dumon S, Santos S, Debierre-Grockiego F, Gouilleux-Gruart V, Cocault L, Boucheron C, et al.
Oncogene
. 1999 Aug;
18(29):4191-9.
PMID: 10435632
Activation of the Jak/STAT pathway by cytokines has been shown to regulate differentiation, proliferation or apoptosis in hematopoeitic cells. Among the Stat proteins, STAT5 is activated by a broad range...
4.
Cocault L, Bouscary D, Le Bousse Kerdiles C, Clay D, Picard F, Gisselbrecht S, et al.
Blood
. 1996 Sep;
88(5):1656-65.
PMID: 8781421
c-mpl, the cellular homologue of the v-mpl oncogene transduced in the myeloproliferative leukemia virus (MPLV), encodes the receptor for thrombopoietin, a cytokine involved in the proliferation and differentiation of cells...
5.
Porteu F, Rouyez M, Cocault L, Benit L, Charon M, Picard F, et al.
Mol Cell Biol
. 1996 May;
16(5):2473-82.
PMID: 8628315
Thrombopoietin (TPO) is the major regulator of growth and differentiation of megakaryocytes. To identify functionally important regions in the cytoplasmic domain of the TPO receptor, mpl, we introduced wild-type mpl...
6.
Pallard C, Gouilleux F, Benit L, Cocault L, Souyri M, Levy D, et al.
EMBO J
. 1995 Jun;
14(12):2847-56.
PMID: 7796811
Thrombopoietin (TPO) is a newly cloned cytokine which is the major regulator of circulating platelet levels, acting on both proliferation and differentiation of megakaryocytes. We have investigated the ability of...
7.
Vigon I, Dreyfus F, Melle J, Viguie F, Ribrag V, Cocault L, et al.
Blood
. 1993 Aug;
82(3):877-83.
PMID: 8393355
Similar to two other hematopoietic growth factor receptors, the c-fms (macrophage colony-stimulating factor receptor) and the c-kit genes, c-mpl has been discovered through the study of oncogenic retroviruses. Unlike c-fms...
8.
Benit L, Charon M, Cocault L, Wendling F, Gisselbrecht S
Oncogene
. 1993 Mar;
8(3):787-90.
PMID: 8382360
Several motifs are conserved in the extracellular domain of the cloned chains of the recently described cytokine receptor superfamily. One of them, usually close to the transmembrane region, is the...
9.
Vigon I, Mornon J, Cocault L, Mitjavila M, Tambourin P, Gisselbrecht S, et al.
Proc Natl Acad Sci U S A
. 1992 Jun;
89(12):5640-4.
PMID: 1608974
We have cloned the human homolog of the v-mpl oncogene transduced in the myeloproliferative leukemia retrovirus, which presents striking homologies with members of the hematopoietin receptor superfamily. We obtained two...
10.
Fischer S, Wendling F, Boulet I, Cocault L, Soula M, Fagard R, et al.
Oncogene
. 1989 Jul;
4(7):901-5.
PMID: 2474138
Megakaryocytic cell lines derived from mouse bone marrow cells transformed by the Myeloproliferative Leukemia Virus (MPLV) contain elevated levels of p60c-src. Northern blot analysis revealed the presence of a 4...