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L Bourova

Explore the profile of L Bourova including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 8
Citations 36
Followers 0
Related Specialties
Molecular Biology
Endocrinology
Biochemistry
Top 10 Co-Authors
P Svoboda
J Novotny
V Rudajev
J Stohr
F Kolar
L Hejnova
J Teisinger
V Lisy
D Durchankova
T Bengtsson
Published In
J Mol Endocrinol
Physiol Res
J Cell Biochem
J Mol Cell Cardiol
Mol Cell Endocrinol
Affiliations
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Recent Articles
1.
The effect of detergents on trimeric G-protein activity in isolated plasma membranes from rat brain cortex: correlation with studies of DPH and Laurdan fluorescence
Sykora J, Bourova L, Hof M, Svoboda P
Biochim Biophys Acta . 2008 Dec; 1788(2):324-32. PMID: 19071083
The effect of non-ionic detergents on baclofen (GABAB-R agonist)-stimulated G-protein activity was measured as a [(35)S]GTPgammaS binding assay in the plasma membranes (PM) isolated from the brain tissue. The effect...
2.
Subcellular redistribution of trimeric G-proteins--potential mechanism of desensitization of hormone response: internalization, solubilization, down-regulation
Drastichova Z, Bourova L, Lisy V, Hejnova L, Rudajev V, Stohr J, et al.
Physiol Res . 2008 May; 57 Suppl 3:S1-10. PMID: 18481919
Agonist-induced subcellular redistribution of G-protein coupled receptors (GPCR) and of trimeric guanine-nucleotide binding regulatory proteins (G-proteins) represent mechanisms of desensitization of hormone response, which have been studied in our laboratory...
3.
Biochemistry of transmembrane signaling mediated by trimeric G proteins
Svoboda P, Teisinger J, Novotny J, Bourova L, Drmota T, Hejnova L, et al.
Physiol Res . 2004 May; 53 Suppl 1:S141-52. PMID: 15119945
Many extracellular signals are at the cell surface received by specific receptors, which upon activation transduce information to the appropriate cellular effector molecules via trimeric G proteins. The G protein-mediated...
4.
Membrane-Bound and cytosolic forms of heterotrimeric G proteins in young and adult rat myocardium: influence of neonatal hypo- and hyperthyroidism
Novotny J, Bourova L, Kolar F, Svoboda P
J Cell Biochem . 2001 Aug; 82(2):215-24. PMID: 11527147
Membrane and cytosolic fractions prepared from ventricular myocardium of young (21-day-old) hypo- or hyperthyroid rats and adult (84-day-old) previously hypo- or hyperthyroid rats were analyzed by immunoblotting with specific anti-G-protein...
5.
Differentiation of cultured brown adipocytes is associated with a selective increase in the short variant of g(s)alpha protein. Evidence for higher functional activity of g(s)alphaS
Bourova L, Pesanova Z, Novotny J, Bengtsson T, Svoboda P
Mol Cell Endocrinol . 2000 Sep; 167(1-2):23-31. PMID: 11000517
In order to examine whether the differentiation process in brown adipocytes cultivated in primary culture is associated with substantial alterations in the complement of G proteins, the levels of these...
6.
Resolution and identification of Gq/G11alpha and Gialpha/Goalpha proteins in brown adipose tissue: effect of cold acclimation
Bourova L, Novotny J, Svoboda P
J Mol Endocrinol . 1999 Oct; 23(2):223-9. PMID: 10514559
Levels of guanine nucleotide-binding proteins G(q)alpha and G(11)alpha, which produce receptor regulation of phospholipase C, were measured immunologically in purified plasma membrane fractions of hamster brown adipose tissue (BAT). This...
7.
G proteins, beta-adrenoreceptors and beta-adrenergic responsiveness in immature and adult rat ventricular myocardium: influence of neonatal hypo- and hyperthyroidism
Novotny J, Bourova L, Malkova O, Svoboda P, Kolar F
J Mol Cell Cardiol . 1999 May; 31(4):761-72. PMID: 10329204
Thyroid hormones influence a wide range of physiological responses and the heart is considered a major target organ for triiodothyronine action. In the present study we examined closely the presumed...
8.
The decrease in the short variant of gsalpha protein is associated with an increase in [3H]CGP12177 binding, [3H]ouabain binding and Na, K-ATPase activity in brown adipose tissue plasma membranes of cold-acclimated hamsters
Bourova L, Novotn J, Svoboda P
J Mol Endocrinol . 1999 Jan; 22(1):55-64. PMID: 9924180
Sucrose density gradient purified plasma membranes isolated from brown adipose tissue of cold-acclimated hamsters (4-10 weeks at 0-4 degreesC) were analysed for the content of the short (GsalphaS) and long...