L A Wolfe
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Explore the profile of L A Wolfe including associated specialties, affiliations and a list of published articles.
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54
Citations
350
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Recent Articles
1.
Burke E, Frucht S, Thompson K, Wolfe L, Yokoyama T, Bertoni M, et al.
Clin Genet
. 2017 Nov;
93(3):712-718.
PMID: 29120065
Mitochondrial aminoacyl-tRNA synthetases (mtARSs) are essential, ubiquitously expressed enzymes that covalently attach amino acids to their corresponding tRNA molecules during translation of mitochondrial genes. Deleterious variants in the mtARS genes...
2.
Bonilla Guerrero R, Wolfe L, Payne N, Tortorelli S, Matern D, Rinaldo P, et al.
J Inherit Metab Dis
. 2008 Dec;
31 Suppl 2:S453-6.
PMID: 19089597
We report a 16-month-old asymptomatic male with enzyme confirmed isovaleric acidaemia (IVA; isovaleryl-CoA dehydrogenase deficiency; OMIM 243500) who, upon routine nutritional follow-up, presented evidence of peroxisomal dysfunction. The newborn screen...
3.
Wigglesworth M, Wolfe L, Wise A
Ernst Schering Found Symp Proc
. 2007 Aug;
(2):105-43.
PMID: 17703580
Drug discovery has successfully exploited the superfamily of seven transmembrane receptors (7TMR), with over 35% of clinically marketed drugs targeting them. However, it is clear that there remains an undefined...
4.
Heenan A, Wolfe L
Can J Physiol Pharmacol
. 2003 Nov;
81(9):839-47.
PMID: 14614519
This study tested the hypothesis that plasma osmolality and the strong ion difference ([SID]) predict PaCO2 during rest and during exercise in physically active pregnant (n = 22; gestational age...
5.
Preston R, Heenan A, Wolfe L
Am J Physiol Regul Integr Comp Physiol
. 2001 Feb;
280(2):R481-7.
PMID: 11208578
In accordance with Stewart's physicochemical approach, the three independent determinants of plasma hydrogen ion concentration ([H(+)]) were measured at rest and during exercise in the follicular (FP) and luteal phase...
6.
Heenan A, Wolfe L, Davies G
Obstet Gynecol
. 2001 Jan;
97(1):127-34.
PMID: 11152921
Objective: To study the effects of human pregnancy on metabolic and respiratory responses to maximal cycle ergometer testing and to test the hypothesis that the respiratory exchange ratio at maximal...
7.
Avery N, Wolfe L, Amara C, Davies G, McGrath M
J Appl Physiol (1985)
. 2001 Jan;
90(1):321-8.
PMID: 11133925
This study examined the effects of human pregnancy on heart rate variability (HRV), spontaneous baroreflex (SBR) sensitivity, and plasma catecholamines at rest and during exercise. Subjects were 14 healthy, physically...
8.
MacPhail A, Davies G, Victory R, Wolfe L
Obstet Gynecol
. 2000 Sep;
96(4):565-70.
PMID: 11004360
Objective: To determine the fetal response to and safety of maximal maternal exercise in the third trimester. Methods: Twenty-three active women with uncomplicated pregnancies (singleton gestations) underwent maximal exercise testing...
9.
Heenan A, Wolfe L
J Appl Physiol (1985)
. 2000 Jan;
88(1):149-57.
PMID: 10642375
Stewart's physicochemical approach was used to study the effects of pregnancy on acid-base regulation in arterialized blood. Responses of 15 healthy pregnant women (PG; gestational age, 37.1 +/- 0.2 wk)...
10.
Wolfe L, Preston R, Burggraf G, McGrath M
Can J Physiol Pharmacol
. 1999 Dec;
77(11):909-17.
PMID: 10593665
This study examined the interactive effects of pregnancy and aerobic conditioning on maternal cardiac structure and function. Effects of closely monitored cycle ergometer conditioning were studied during the second (TM2)...