L A Chodosh
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Explore the profile of L A Chodosh including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
2197
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Recent Articles
1.
Turpin J, Ling C, Crosby E, Hartman Z, Simond A, Chodosh L, et al.
Oncogene
. 2016 May;
35(47):6053-6064.
PMID: 27157621
Amplification and overexpression of erbB2/neu proto-oncogene is observed in 20-30% human breast cancer and is inversely correlated with the survival of the patient. Despite this, somatic activating mutations within erbB2...
2.
Magnitsky S, Belka G, Sterner C, Pickup S, Chodosh L, Glickson J
NMR Biomed
. 2012 Jul;
26(1):35-42.
PMID: 22767445
This study compared the steady state concentration of lactate in an inducible Her2/nue transgenic breast cancer mouse model and in tumours from the same Her2/neu model grown orthotopically. In vivo...
3.
Buratowski S, Chodosh L
Curr Protoc Pharmacol
. 2011 Oct;
Chapter 6:Unit6.8.
PMID: 21959763
DNA-binding assay using nondenaturing polyacrylamide gel electrophoresis (PAGE) provides a simple, rapid, and extremely sensitive method for detecting sequence-specific DNA-binding proteins. Proteins that bind specifically to an end-labeled DNA fragment...
4.
Connelly L, Barham W, Onishko H, Sherrill T, Chodosh L, Blackwell T, et al.
Oncogene
. 2010 Nov;
30(12):1402-12.
PMID: 21076466
The transcription factor nuclear factor kappa B (NF-κB) is activated in human breast cancer tissues and cell lines. However, it is unclear whether NF-κB activation is a consequence of tumor...
5.
Zeng X, Shaikh F, Harrison M, Adon A, Trimboli A, Carroll K, et al.
Oncogene
. 2010 Jun;
29(36):5103-12.
PMID: 20581865
Centrosome amplification (CA) contributes to carcinogenesis by generating aneuploidy. Elevated frequencies of CA in most benign breast lesions and primary tumors suggest a causative role for CA in breast cancers....
6.
Chodosh L, Buratowski S
Curr Protoc Protein Sci
. 2008 Apr;
Chapter 9:Unit 9.7.
PMID: 18429216
This unit presents purification protocols that exploit the tight and essentially irreversible complex that biotin forms with streptavidin. A DNA fragment containing a high-affinity binding site for the protein of...
7.
Chodosh L
Curr Protoc Mol Biol
. 2008 Feb;
Chapter 12:Unit 12.6.
PMID: 18265089
Short fragments of DNA-either natural or formed from oligonucleotides-containing a high-affinity site for a DNA-binding protein provide a powerful tool for purification. The biotin/streptavidin purification system is based on the...
8.
Chodosh L
Curr Protoc Mol Biol
. 2008 Feb;
Chapter 12:Unit 12.5.
PMID: 18265088
Irradiation of protein-nucleic acid complexes with ultraviolet light causes covalent bonds to form between the nucleic acid and proteins that are in close contact with the nucleic acid. Thus, UV...
9.
Buratowski S, Chodosh L
Curr Protoc Mol Biol
. 2008 Feb;
Chapter 12:Unit 12.2.
PMID: 18265085
The DNA-binding assay using nondenaturing polyacrylamide gel electrophoresis (PAGE) provides a simple, rapid, and extremely sensitive method for detecting sequence-specific DNA-binding proteins. Proteins that bind specifically to an end-labeled DNA...
10.
Jones R, Campbell C, Gunther E, Chodosh L, Petrik J, Khokha R, et al.
Oncogene
. 2006 Sep;
26(11):1636-44.
PMID: 16953219
Overexpression and hyperactivation of the type I insulin-like growth factor receptor (IGF-IR) has been observed in human breast tumor biopsies. In addition, in vitro studies indicate that overexpression of IGF-IR...