Kyu Kwang Kim
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Explore the profile of Kyu Kwang Kim including associated specialties, affiliations and a list of published articles.
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33
Citations
402
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Recent Articles
11.
Kim K, Abelman S, Yano N, Ribeiro J, Singh R, Tipping M, et al.
Sci Rep
. 2015 Oct;
5:14296.
PMID: 26469226
Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor that triggers adaptive responses upon low oxygen conditions and plays a crucial role in cancer metabolism and therapy resistance. Tetrathiomolybdate (TM), a therapy...
12.
Kim K, Lange T, Singh R, Brard L, Moore R
BMC Cancer
. 2012 Apr;
12:147.
PMID: 22502731
Background: Our recent study showed that tetrathiomolybdate (TM), a drug to treat copper overload disorders, can sensitize drug-resistant endometrial cancer cells to reactive oxygen species (ROS)-generating anticancer drug doxorubicin. To...
13.
Kim K, Singh A, Singh R, DeMartino A, Brard L, Vorsa N, et al.
Int J Oncol
. 2011 Sep;
40(1):227-35.
PMID: 21922132
Cranberry extracts may provide beneficial health effects in the treatment of various diseases, including cancer. However, the underlying molecular mechanisms of antineoplastic properties are not understood. We report the effect...
14.
Horan T, Zompa M, Seto C, Kim K, Moore R, Lange T
Invest New Drugs
. 2011 Aug;
30(4):1460-70.
PMID: 21809024
The objective of the present study was to determine the in-vitro effect of Abietyl-Isothiocyanate (ABITC), a representative of a new class of anti-cancer drugs, on endometrial cancer (EC) cell lines....
15.
Brard L, Lange T, Robison K, Kim K, Ara T, McCallum M, et al.
Gynecol Oncol
. 2011 Aug;
123(2):370-8.
PMID: 21803404
Objective: In human trials calcitriol and its analogs displayed unacceptable systemic toxicities including hypercalcemia. This study was designed to evaluate a novel non-hypercalcemic vitamin-D derivative (MT19c) and its anticancer effects...
16.
Kim K, Singh R, Strongin R, Moore R, Brard L, Lange T
PLoS One
. 2011 May;
6(4):e19049.
PMID: 21559503
The objective of the present study was to investigate the specific effects of Iron(III)-salophene (Fe-SP) on viability, morphology, proliferation, cell cycle progression, ROS generation and pro-apoptotic MAPK activation in neuroblastoma...
17.
Hwang J, Yoo H, Song H, Kim K, Chun Y, Matsui T, et al.
Nutr Cancer
. 2011 May;
63(4):645-52.
PMID: 21547849
Chungkookjang is a Korean fermented soybean containing microorganisms, proteinase, and diverse bioactive compounds, including a high concentration of isoflavones and peptides. Growth of breast cancer MCF7 cells decreased dependent on...
18.
Singh R, Dorf L, DeMartino A, Illenye S, Koto K, Currier E, et al.
Cancer Biol Ther
. 2011 May;
11(12):1036-45.
PMID: 21532338
Patients diagnosed with high-risk neuroblastoma (NB), an extracranial solid tumor in children, have metastases and low survival (30%) despite aggressive multi-modal therapy. Therefore new therapies are urgently needed. We show...
19.
Kim K, Kawar N, Singh R, Lange T, Brard L, Moore R
Gynecol Oncol
. 2011 May;
122(1):183-9.
PMID: 21529906
Objective: Doxorubicin is a potent anti-cancer agent with efficacy against a broad range of tumors, including endometrial cancer. Doxorubicin produces reactive oxygen species (ROS) resulting in cytotoxicity. Tetrathiomolybdate (TM), a...
20.
Kim K, Lange T, Singh R, Brard L
BMC Cancer
. 2010 Feb;
10:72.
PMID: 20184758
Background: Metal chelators have gained much attention as potential anti-cancer agents. However, the effects of chelators are often linked solely to their capacity to bind iron while the potential complexation...