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Kyril Turpaev

Explore the profile of Kyril Turpaev including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 78
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Recent Articles
1.
Turpaev K, Bovt E, Shakhidzhanov S, Sinauridze E, Smetanina N, Koleva L, et al.
Front Physiol . 2025 Feb; 16:1497588. PMID: 40008208
Hereditary spherocytosis is a common hemolytic anemia with different severity. The causes of hereditary spherocytosis are mutations in genes that encode red blood cell (RBC) membrane and cytoskeletal proteins, including...
2.
Elksnis A, Schiffer T, Palm F, Wang Y, Cen J, Turpaev K, et al.
Clin Sci (Lond) . 2021 Sep; 135(19):2243-2263. PMID: 34569605
The protein tyrosine kinase inhibitor imatinib is used in the treatment of various malignancies but may also promote beneficial effects in the treatment of diabetes. The aim of the present...
3.
Turpaev K, Krizhanovskii C, Wang X, Sargsyan E, Bergsten P, Welsh N
FASEB J . 2018 Nov; 33(3):3510-3522. PMID: 30462531
The naturally occurring quassinoid compound brusatol improves the survival of insulin-producing cells when exposed to the proinflammatory cytokines IL-1β and IFN-γ in vitro. The aim of the present study was...
4.
Turpaev K, Welsh N
Eur J Pharmacol . 2016 May; 784:69-80. PMID: 27178899
We presently report that treatment with tyrphostin AG-126 (2-(3-hydroxy-4-nitrobenzylidene)malononitrile) and ten other aromatic malononitrile compounds (AMN) improves the resistance of insulin-producing βTC6, RIN-5AH, and MIN6 cells to oxidative stress and...
5.
Turpaev K, Welsh N
Biochem Biophys Res Commun . 2015 Apr; 460(3):868-72. PMID: 25824046
Brusatol is a natural terpenoid that is capable of inducing a variety of biological effects. We presently report that this substance dramatically improves beta-cell survival when exposed to pro-inflammatory cytokines...
6.
Ngamjariyawat A, Turpaev K, Vasylovska S, Kozlova E, Welsh N
PLoS One . 2013 Apr; 8(4):e61828. PMID: 23613946
Purpose: Transplantation of pancreatic islets to Type 1 diabetes patients is hampered by inflammatory reactions at the transplantation site leading to dysfunction and death of insulin producing beta-cells. Recently we...
7.
Ngamjariyawat A, Turpaev K, Welsh N, Kozlova E
Pancreas . 2012 Mar; 41(3):490-2. PMID: 22415669
No abstract available.
8.
Turpaev K, Ermolenko M, Cresteil T, Drapier J
Biochem Pharmacol . 2011 Jun; 82(5):535-47. PMID: 21669191
Benzylidenemalononitrile (BMN) tyrphostins are well known as potent tyrosine kinase inhibitors. Moreover, in recent years it has been recognized that members of the tyrphostin family possess additional biological activities independent...
9.
Turpaev K, Glatigny A, Bignon J, Delacroix H, Drapier J
Free Radic Biol Med . 2009 Nov; 48(2):298-305. PMID: 19892011
We examined early and late alterations in gene expression patterns and phosphorylation levels of key regulators of selected signaling pathways in U937 cells exposed to various (*)NO fluxes. cDNA microarray...
10.
Turpaev K, Drapier J
Eur J Pharmacol . 2009 Apr; 606(1-3):1-8. PMID: 19374863
Tyrphostins are well-established selective inhibitors of protein tyrosine kinase activity of EGF receptor and other growth factor receptors. Unexpectedly, we found that, in U-937 monocytic cells, tyrphostin AG-126 augments the...