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Kyoung Jin Lee

Explore the profile of Kyoung Jin Lee including associated specialties, affiliations and a list of published articles. Areas
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Articles 66
Citations 862
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Recent Articles
1.
Moon T, Kang I, Lee K, Kim J, Kim H, Han A, et al.
Mol Ther Methods Clin Dev . 2025 Feb; 33(1):101404. PMID: 39897639
Hypoxic retinopathies, including diabetic retinopathy, are major contributors to vision impairment, mainly due to accelerated angiogenesis and inflammation. Previously, we demonstrated that AAV2-shmTOR, effective across distinct species, holds therapeutic promise...
2.
Chang H, Lee K, Park M, Woo H, Kim J, Kang I, et al.
Neurotherapeutics . 2024 Dec; 22(2):e00511. PMID: 39674763
Tetrahydrobiopterin (BH4) expression is normally strictly controlled; however, its intracellular levels increase considerably following nerve damage. GTP cyclohydrolase I (GCH1) plays a crucial role in regulating BH4 concentration, with an...
3.
Lee K, Lee J
Bioinspir Biomim . 2024 Oct; 19(6). PMID: 39366423
Soft peristaltic pumps, which use soft ring actuators instead of mechanical pistons or rollers, offer advantages in transporting liquids with non-uniform solids, such as slurry, food, and sewage. Recent advances...
4.
Han A, Moon T, Kang I, Yu D, Kim Y, Byon C, et al.
BMB Rep . 2023 Dec; 57(6):281-286. PMID: 38053296
Adult hippocampal neurogenesis plays a pivotal role in maintaining cognitive brain function. However, this process diminishes with age, particularly in patients with neurodegenerative disorders. While small, non-coding microRNAs (miRNAs) are...
5.
Lee K, Lee J
Technol Health Care . 2023 Oct; 32(3):1351-1360. PMID: 37781825
Background: Elastomeric pumps have a curved infusion rate profile over infusion time. Chemically driven pumps can overcome such limitations of elastomeric pumps and infuse constantly. However, studies on the pharmacokinetic...
6.
Lee E, Lee K, Jung S, Park K, Park S
Bone Res . 2023 Apr; 11(1):22. PMID: 37085481
Myeloid-derived suppressor cells (MDSCs) are bone marrow (BM)-derived immunosuppressive cells in the tumor microenvironment, but the mechanism of MDSC mobilization from the BM remains unclear. We investigated how BM stromal...
7.
Kang J, Lee D, Lee K, Yoon J, Kwon J, Seo Y, et al.
Cancers (Basel) . 2022 Jun; 14(12). PMID: 35740547
Myeloid-derived suppressor cells (MDSCs) and M2 macrophages in the tumor microenvironment contribute to tumor progression by inducing immune tolerance to tumor antigens and cancer cells. Metformin, one of the most...
8.
Lee S, Lee J, Choi J, Kim H, Kim J, Cha S, et al.
PLoS One . 2022 Jun; 17(6):e0269951. PMID: 35709240
In addition to laser photocoagulation, therapeutic interventions for diabetic retinopathy (DR) have heretofore consisted of anti-VEGF drugs, which, besides drawbacks inherent to the treatments themselves, are limited in scope and...
9.
Jeong M, Jeong M, Kim J, Cho S, Lee K, Park S, et al.
Sci Rep . 2021 Oct; 11(1):20812. PMID: 34675258
Translationally controlled tumor protein (TCTP) is expressed in many tissues, particularly in human tumors. It plays a role in malignant transformation, apoptosis prevention, and DNA damage repair. The signaling mechanisms...
10.
Lee K, Lee S, Woo H, Cho H, Yu D, Jeong S, et al.
PLoS One . 2020 Jul; 15(7):e0235356. PMID: 32628693
As a new class of cancer therapeutic agents, oncolytic viruses (OVs) have gained much attention not only due to their ability to selectively replicate in and lyse tumor cells, but...