Kyosuke Mukae
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Explore the profile of Kyosuke Mukae including associated specialties, affiliations and a list of published articles.
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15
Citations
105
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Recent Articles
1.
Okada R, Takenobu H, Satoh S, Sugino R, Onuki R, Haruta M, et al.
Genes Cells
. 2024 Aug;
29(10):838-853.
PMID: 39189159
Epigenetic alterations critically affect tumor development. Polycomb-group complexes constitute an evolutionarily conserved epigenetic machinery that regulates stem cell fate and development. They are implicated in tumorigenesis, primarily via histone modification....
2.
Sakil M, Mukae K, Bao J, Sadhu A, Roni M, Inoue-Aono Y, et al.
Plant Cell Physiol
. 2023 Nov;
65(2):269-281.
PMID: 38029282
The autophagy-defective mutants (atg5 and atg7) of Physcomitrium patens exhibit strong desiccation tolerance. Here, we examined the effects of H2O2 on wild-type (WT) and autophagy-defective mutants of P. patens, considering...
3.
Development of RNA/DNA automated extraction and purification device for infectious disease diagnosis
Mukae K, Takei O, Imai F, Kamijo T
Pract Lab Med
. 2023 Sep;
37:e00335.
PMID: 37693633
Genetic tests using RNA/DNA are the most accurate for diagnosing infectious diseases and assessing disease susceptibility, including COVID-19. However, manual specimen handling and the risk of secondary infections by medical...
4.
Parvin S, Akter J, Takenobu H, Katai Y, Satoh S, Okada R, et al.
BMC Cancer
. 2023 Apr;
23(1):313.
PMID: 37020276
Background: Genomic alterations, including loss of function in chromosome band 11q22-23, are frequently observed in neuroblastoma, which is the most common extracranial childhood tumour. In neuroblastoma, ATM, a DNA damage...
5.
Mukae K, Takenobu H, Endo Y, Haruta M, Shi T, Satoh S, et al.
Cancer Sci
. 2023 Jan;
114(5):1898-1911.
PMID: 36661413
Mesenchymal stem cell- or osteoblast-derived osteosarcoma is the most common malignant bone tumor. Its highly metastatic malignant phenotypes, which are often associated with a poor prognosis, have been correlated with...
6.
Akita N, Okada R, Mukae K, Sugino R, Takenobu H, Chikaraishi K, et al.
Exp Cell Res
. 2022 Nov;
422(1):113412.
PMID: 36370852
The overexpression of BMI1, a polycomb protein, correlates with cancer development and aggressiveness. We previously reported that MYCN-induced BMI1 positively regulated neuroblastoma (NB) cell proliferation via the transcriptional inhibition of...
7.
Roni M, Sakil M, Aktar M, Takatsuka C, Mukae K, Inoue-Aono Y, et al.
Plants (Basel)
. 2022 Sep;
11(17).
PMID: 36079662
Leaf senescence accompanied by yellowing and Rubisco degradation occurs prematurely in response to various stresses. However, signaling pathways between stress perception and senescence responses are not understood fully, although previous...
8.
Shinno Y, Takenobu H, Sugino R, Endo Y, Okada R, Haruta M, et al.
Cancer Sci
. 2022 Sep;
113(12):4193-4206.
PMID: 36052716
In the present study, we found that EZH1 depletion in MYCN-amplified neuroblastoma cells resulted in significant cell death as well as xenograft inhibition. EZH1 depletion decreased the level of H3K27me1;...
9.
Sakil M, Mukae K, Funada R, Kotake T, Ueno S, Aktar M, et al.
Plants (Basel)
. 2022 Aug;
11(16).
PMID: 36015461
The physiological implications of autophagy in plant cells have not been fully elucidated. Therefore, we investigated the consequences of autophagy in the moss Physcomitrella by measuring biochemical parameters (fresh and...
10.
Akter J, Katai Y, Sultana P, Takenobu H, Haruta M, Sugino R, et al.
Oncogenesis
. 2021 Nov;
10(11):73.
PMID: 34743173
Genetic aberrations are present in the ATRX gene in older high-risk neuroblastoma (NB) patients with very poor clinical outcomes. Its loss-of-function (LoF) facilitates the alternative lengthening of telomeres (ALT) pathway...