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Kyle Wang

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Recent Articles
1.
Upadhyay R, Elguindy A, Salts L, Donovan K, Sengupta S, Wang K, et al.
Int J Radiat Oncol Biol Phys . 2025 Feb; PMID: 39993542
Purpose: Radiation necrosis (RN) is a dose-limiting toxicity of stereotactic radiosurgery (SRS) for brain metastases. Oral corticosteroids are not optimal for long-term management, given multiple side effects. Boswellia serrata (BS)...
2.
Longhurst A, Wang K, Suresh H, Ketavarapu M, Ward H, Jones I, et al.
Elife . 2025 Feb; 13. PMID: 39903505
Progression through the G1 phase of the cell cycle is the most highly regulated step in cellular division. We employed a chemogenetic approach to discover novel cellular networks that regulate...
3.
Bhattacharya D, Barrile R, Toukam D, Gawali V, Kallay L, Ahmed T, et al.
Cancers (Basel) . 2024 Sep; 16(18. PMID: 39335139
In non-small cell lung cancer (NSCLC) treatment, radiotherapy responses are not durable and toxicity limits therapy. We find that AM-101, a synthetic benzodiazepine activator of GABA(A) receptor, impairs the viability...
4.
Kaye J, Na J, Atluri S, Ivey N, Zack A, Chaudhary R, et al.
World Neurosurg . 2024 Jun; 189:203-208. PMID: 38901486
Background: World Health Organization grade II/III meningiomas frequently recur despite maximal safe surgical resection and adjuvant radiation. Notoriously resistant to medical therapy, no well-established guidelines for pharmacologic treatment currently exist....
5.
Longhurst A, Wang K, Suresh H, Ketavarapu M, Ward H, Jones I, et al.
bioRxiv . 2024 Apr; PMID: 38562687
Progression through the G1 phase of the cell cycle is the most highly regulated step in cellular division. We employed a chemogenetic approach to discover novel cellular networks that regulate...
6.
Razdaibiedina A, Brechalov A, Friesen H, Mattiazzi Usaj M, Masinas M, Suresh H, et al.
Mol Syst Biol . 2024 Mar; 20(5):521-548. PMID: 38472305
Fluorescence microscopy data describe protein localization patterns at single-cell resolution and have the potential to reveal whole-proteome functional information with remarkable precision. Yet, extracting biologically meaningful representations from cell micrographs...
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Bhattacharya D, Barille R, Toukam D, Gawali V, Kallay L, Ahmed T, et al.
bioRxiv . 2023 Dec; PMID: 38076805
Highlights: Activating GABA(A) receptors intrinsic to lung primary and metastatic brain cancer cells triggers a cytotoxic response. GABA(A) receptor activation works as well as chemotherapeutic docetaxel in impairing lung cancer...
9.
Dandage R, Papkov M, Greco B, Fishman D, Friesen H, Wang K, et al.
bioRxiv . 2023 Dec; PMID: 38045359
Gene duplication is common across the tree of life, including yeast and humans, and contributes to genomic robustness. In this study, we examined changes in the subcellular localization and abundance...
10.
Hall J, Lui K, Tan X, Shumway J, Collichio F, Moschos S, et al.
Radiother Oncol . 2023 Sep; 189:109920. PMID: 37769968
Background And Purpose: Emerging data suggest immune checkpoint inhibitors (ICI) and stereotactic radiosurgery (SRS) or radiotherapy (SRT) may work synergistically, potentially increasing both efficacy and toxicity. This manuscript characterizes factors...