Kyle Osborne
Overview
Explore the profile of Kyle Osborne including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
4
Citations
40
Followers
0
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Top 10 Co-Authors
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Recent Articles
1.
Ginley-Hidinger M, Abewe H, Osborne K, Richey A, Kitchen N, Mortenson K, et al.
Cell Genom
. 2024 Apr;
4(5):100542.
PMID: 38663407
Cis-regulatory elements control transcription levels, temporal dynamics, and cell-cell variation or transcriptional noise. However, the combination of regulatory features that control these different attributes is not fully understood. Here, we...
2.
Ginley-Hidinger M, Abewe H, Osborne K, Richey A, Kitchen N, Mortenson K, et al.
bioRxiv
. 2023 Mar;
PMID: 36993565
Cis-regulatory elements control transcription levels, temporal dynamics, and cell-cell variation or transcriptional noise. However, the combination of regulatory features that control these different attributes is not fully understood. Here, we...
3.
Benitez E, Lomova Kaufman A, Cervantes L, Clark D, Ayoub P, Senadheera S, et al.
Front Genome Ed
. 2021 Oct;
2:601541.
PMID: 34713224
Monogenic disorders of the blood system have the potential to be treated by autologous stem cell transplantation of genetically modified hematopoietic stem and progenitor cells (HSPCs). The sgRNA/Cas9 system allows...
4.
Masiuk K, Zhang R, Osborne K, Hollis R, Campo-Fernandez B, Kohn D
Mol Ther Methods Clin Dev
. 2019 Apr;
13:390-398.
PMID: 31024981
Lentiviral vector (LV)-based hematopoietic stem and progenitor cell (HSPC) gene therapy is becoming a promising alternative to allogeneic stem cell transplantation for curing genetic diseases. Clinical trials are currently underway...