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Kyeong Hwa Sim

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Articles 8
Citations 35
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Recent Articles
1.
Sim K, Park K, Lee C, Lee Y
Chemosphere . 2025 Jan; 372:144119. PMID: 39827624
Perfluorooctane sulfonate (PFOS), a widely distributed and persistent organic pollutant, is known to cause immune dysfunction. In a previous study, we reported that PFOS modestly increases mast cell activation. However,...
2.
Sim K, Lee E, Shrestha P, Choi B, Hong J, Lee Y
Biochem Pharmacol . 2024 Dec; 232:116698. PMID: 39643121
Isobavachin, isolated from Psoralea corylifolia L. exhibits therapeutic potential for osteoporosis or skin disease. Here, we evaluated the pharmacological effects of isobavachin on IgE-dependent inflammatory allergic reactions, as well as...
3.
Kwon K, Kim E, Sim K, Lee Y, Kang E, Han K, et al.
Sci Rep . 2024 May; 14(1):12226. PMID: 38806600
The human microbiome contains genetic information that regulates metabolic processes in response to host health and disease. While acidic vaginal pH is maintained in normal conditions, the pH level increases...
4.
Sim K, Oh H, Lee C, Eun H, Lee Y
Int J Environ Res Public Health . 2023 Oct; 20(19). PMID: 37835138
Perfluorohexane sulfonate (PFHxS) is a widely detected replacement for legacy long-chain perfluoroalkyl substances (PFAS) in the environment and human blood samples. Its potential toxicity led to its recent classification as...
5.
Choi B, Ryoo I, Sim K, Ahn H, Lee Y, Kwak M
Biomol Ther (Seoul) . 2022 Jun; 30(4):368-379. PMID: 35768333
Hyaluronic acid (HA), a ligand of CD44, accumulates in some types of tumors and is responsible for tumor progression. The nuclear factor erythroid 2-like 2 (NRF2) regulates cytoprotective genes and...
6.
Sim K, Lee Y
Chemosphere . 2021 Oct; 288(Pt 1):132503. PMID: 34626661
Perfluorohexane sulfonate (PFHxS) is a widely used industrial chemical detected in human umbilical cord blood and breast milk, and has been suggested to exhibit developmental neurotoxicity. Previous studies on mice...
7.
Park S, Sim K, Shrestha P, Yang J, Lee Y
Food Chem Toxicol . 2021 Aug; 156:112478. PMID: 34363875
Perfluoroalkyl compounds (PFCs) as food contaminants are widely distributed persistent organic pollutants (POPs) and have been suggested to induce immune dysfunction. However, their effects on immune function are not conclusive....
8.
Triningsih D, Yang J, Sim K, Lee C, Lee Y
Toxicol In Vitro . 2021 Feb; 72:105105. PMID: 33545342
Acrylamide is known as a neurotoxicant found in commonly consumed food as well as in human body. However, the underlying mechanisms involved in neurotoxicity by acrylamide and its metabolite, glycidamide...
9.
Lee Y, Shu M, Kim J, Kim Y, Sim K, Sung W, et al.
PLoS One . 2019 Jan; 14(1):e0211415. PMID: 30695051
Alcoholic liver disease (ALD) is a worldwide health problem and hepatocyte apoptosis has been associated with the development/progression of ALD. However, no definite effective pharmacotherapy for ALD is currently available....