Kyeong Ah Park
Overview
Explore the profile of Kyeong Ah Park including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
497
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0
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Recent Articles
1.
Park K, Jung C, Sohn K, Ju E, Shin S, Park I, et al.
Heliyon
. 2024 Mar;
10(6):e28092.
PMID: 38533031
Ubiquitination of RIPK1 plays an essential role in the recruitment of the IKK complex, an upstream component of pro-survival NF-κB. It also limits TNF-induced programmed cell death by inhibiting the...
2.
Ju E, Park K, Shen H, Hur G
Exp Mol Med
. 2022 Sep;
54(9):1401-1411.
PMID: 36171264
Receptor-interacting serine threonine protein kinase 1 (RIPK1) has emerged as a central molecular switch in controlling the balance between cell survival and cell death. The pro-survival role of RIPK1 in...
3.
Byun H, Ju E, Park K, Sohn K, Jung C, Hong J, et al.
Cell Biol Toxicol
. 2022 Sep;
39(4):1677-1696.
PMID: 36163569
The activation of receptor-interacting protein kinase 1 (RIPK1) by death-inducing signaling complex (DISC) formation is essential for triggering the necroptotic mode of cell death under apoptosis-deficient conditions. Thus, targeting the...
4.
Won M, Park K, Kim S, Ju E, Ko Y, Yoo H, et al.
Cell Death Differ
. 2021 Nov;
29(6):1152-1163.
PMID: 34839354
In TNF signaling, ubiquitination of RIP1 functions as an early cell-death checkpoint, which prevents the spatial transition of the signaling complex from complex-I to death-inducing complex-II. Here, we report that...
5.
Piao X, Byun H, Lee S, Ju E, Park K, Sohn K, et al.
Biochem Pharmacol
. 2021 Aug;
192:114733.
PMID: 34411570
In tumor necrosis factor (TNF) signaling, IκB kinase (IKK) complex-mediated activation of NF-κB is a well-known protective mechanism against cell death via transcriptional induction of pro-survival genes occurring as a...
6.
Kang K, Quan K, Byun H, Lee S, Piao X, Ju E, et al.
FASEB J
. 2020 Feb;
34(3):4369-4383.
PMID: 32027418
In tumor necrosis factor (TNF) signaling, phosphorylation and activation of receptor interacting protein kinase 1 (RIPK1) by upstream kinases is an essential checkpoint in the suppression of TNF-induced cell death....
7.
Lee S, Sohn K, Choi D, Won M, Park K, Ju S, et al.
Mol Ther Nucleic Acids
. 2016 Sep;
5(9):e367.
PMID: 27673563
Controlled gene expression is an indispensable technique in biomedical research. Here, we report a convenient, straightforward, and reliable way to induce expression of a gene of interest with negligible background...
8.
Kang K, Won M, Yuk J, Park C, Byun H, Park K, et al.
Biochem Pharmacol
. 2016 Sep;
121:52-66.
PMID: 27664853
A specific small-molecule inhibitor of the TLR4 signaling complex upstream of the IKK would likely provide therapeutic benefit for NF-κB-mediated inflammatory disease. We previously identified brazilin as a selective upstream...
9.
Won M, Byun H, Park K, Hur G
Arch Pharm Res
. 2016 Jun;
39(8):1075-84.
PMID: 27287455
The transcription factor nuclear factor-kappa B (NF-κB) controls a number of essential cellular functions, including the immune response, cell proliferation, and apoptosis. NF-κB signaling must be engaged temporally and spatially...
10.
Lee Y, Byun H, Seok J, Park K, Won M, Seo W, et al.
Sci Rep
. 2016 Apr;
6:25094.
PMID: 27117478
Death receptor (DR) ligation elicits two different modes of cell death (necroptosis and apoptosis) depending on the cellular context. By screening a plant extract library from cells undergoing necroptosis or...