Kuzhali Muthumalaiappan
Overview
Explore the profile of Kuzhali Muthumalaiappan including associated specialties, affiliations and a list of published articles.
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13
Citations
89
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Recent Articles
1.
Nair R, Subramaniam V, Barwick B, Gupta V, Matulis S, Lonial S, et al.
Haematologica
. 2022 May;
107(9):2226-2231.
PMID: 35511673
No abstract available.
2.
Burmeister D, Smith S, Muthumalaiappan K, Hill D, Moffatt L, Carlson D, et al.
J Burn Care Res
. 2020 Dec;
42(2):113-125.
PMID: 33306095
On June 17 to 18, 2019, the American Burn Association, in conjunction with Underwriters Laboratories, convened a group of experts on burn resuscitation in Washington, DC. The goal of the...
3.
Walczak J, Hasan S, Shoaee N, Tromblay D, Muthumalaiappan K
Shock
. 2020 Sep;
55(6):766-774.
PMID: 32890311
Introduction: In this study, using burn patient's peripheral blood mononuclear cells (PBMCs), we have shown that the Epo independent stage of terminal enucleation to reticulocyte formation is impeded in the...
4.
Walczak J, Bunn C, Saini P, Ming Liu Y, Baldea A, Muthumalaiappan K
J Burn Care Res
. 2020 Aug;
42(2):311-322.
PMID: 32842148
Burn patients experience erythropoietin resistant anemia in which early commitment and late maturation of erythroblasts are defective. The authors previously showed that propranolol (Prop) treatment restores erythroid committed progenitors, but...
5.
Walczak J, Camargo Johnson M, Muthumalaiappan K
Methods Protoc
. 2020 Jul;
3(3).
PMID: 32629835
During erythropoiesis, the molecular chaperone alpha-hemoglobin-stabilizing protein (AHSP) sequesters free alpha-hemoglobin (Hb) and prevents precipitation of excess Hb. While AHSP is linked to hereditary anemia, the pattern of expression during...
6.
Hasan S, Johnson M, Kini A, Baldea A, Muthumalaiappan K
Front Med (Lausanne)
. 2019 Dec;
6:260.
PMID: 31824951
Burn injury has been shown to significantly dampen erythropoiesis in both burn patients and in murine models. Our previous findings elucidated the erythropoietin independent defects in red cell development stages...
7.
8.
Hasan S, Mosier M, Szilagyi A, Gamelli R, Muthumalaiappan K
Surgery
. 2017 Jul;
162(4):901-916.
PMID: 28716301
Background: Anemia of critical illness is resistant to exogenous erythropoietin. Packed red blood cells transfusions is the only treatment option, and despite related cost and morbidity, there is a need...
9.
Hasan S, Mosier M, Conrad P, Szilagyi A, Gamelli R, Muthumalaiappan K
J Burn Care Res
. 2017 Jun;
39(2):286-294.
PMID: 28570310
Mechanisms of erythropoietin (Epo)-resistant anemia in burn patients are poorly understood. We have recently found that administering a nonselective beta 1,2-adrenergic blocker propranolol (PR) was effective in reversing myelo-erythroid commitment...
10.
Hasan S, Johnson N, Mosier M, Shankar R, Conrad P, Szilagyi A, et al.
Am J Physiol Cell Physiol
. 2016 Dec;
312(3):C286-C301.
PMID: 28031160
Severely injured burn patients receive multiple blood transfusions for anemia of critical illness despite the adverse consequences. One limiting factor to consider alternate treatment strategies is the lack of a...