Kutlu O Ulgen
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Explore the profile of Kutlu O Ulgen including associated specialties, affiliations and a list of published articles.
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Articles
55
Citations
457
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Recent Articles
1.
Sertbas M, Ulgen K
OMICS
. 2025 Mar;
PMID: 40068171
Type 2 diabetes (T2D) is characterized by relative insulin deficiency due to pancreatic beta cell dysfunction and insulin resistance in different tissues. Not only beta cells but also other islet...
2.
Ozbek O, Genc D, Ulgen K
ACS Pharmacol Transl Sci
. 2024 Aug;
7(8):2251-2279.
PMID: 39144562
Nanoparticles (NPs) have been widely used to improve the pharmacokinetic properties and tissue distribution of small molecules such as targeting to a specific tissue of interest, enhancing their systemic circulation,...
3.
Ozbek I, Saybasili H, Ulgen K
ACS Biomater Sci Eng
. 2024 Apr;
10(5):2616-2635.
PMID: 38664996
Primary brain tumor is one of the most fatal diseases. The most malignant type among them, glioblastoma (GBM), has low survival rates. Standard treatments reduce the life quality of patients...
4.
Sertbas M, Ulgen K
ACS Omega
. 2024 Apr;
9(13):15535-15546.
PMID: 38585079
Genome-scale metabolic models (GEMs) are promising computational tools that contribute to elucidating host-virus interactions at the system level and developing therapeutic strategies against viral infection. In this study, the effect...
5.
Temizer A, Uludogan G, Ozcelik R, Koulani T, Ozkirimli E, Ulgen K, et al.
Mol Inform
. 2024 Jan;
43(3):e202300249.
PMID: 38196065
Machine learning models have found numerous successful applications in computational drug discovery. A large body of these models represents molecules as sequences since molecular sequences are easily available, simple, and...
6.
Yurdakul E, Barlas Y, Ulgen K
Brain Behav
. 2023 Oct;
13(12):e3273.
PMID: 37807632
Background: The mechanism underlying autism spectrum disorder (ASD) remains incompletely understood, but researchers have identified over a thousand genes involved in complex interactions within the brain, nervous, and immune systems,...
7.
Tas E, Ulgen K
Metabolites
. 2023 May;
13(5).
PMID: 37233633
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder diagnosed with hyperactivity, impulsivity, and a lack of attention inconsistent with the patient's development level. The fact that people with ADHD...
8.
Esvap E, Ulgen K
Biomedicines
. 2023 Feb;
11(2).
PMID: 36831124
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders generally characterized by repetitive behaviors and difficulties in communication and social behavior. Despite its heterogeneous nature, several metabolic dysregulations...
9.
Tezcan E, Demirtas Y, Cakar Z, Ulgen K
Front Bioinform
. 2023 Jan;
3:1121409.
PMID: 36714093
The fungal priority pathogen causes cryptococcal meningoencephalitis in immunocompromised individuals and leads to hundreds of thousands of deaths per year. The undesirable side effects of existing treatments, the need for...
10.
Ozbek I, Ulgen K
Molecules
. 2023 Jan;
28(2).
PMID: 36677837
Medulloblastoma (MB), occurring in the cerebellum, is the most common childhood brain tumor. Because conventional methods decline life quality and endanger children with detrimental side effects, computer models are needed...