Kuniyoshi Iwabuchi
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Explore the profile of Kuniyoshi Iwabuchi including associated specialties, affiliations and a list of published articles.
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34
Citations
1084
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Recent Articles
1.
Horie T, Hirata H, Sakamoto T, Kitajima H, Fuku A, Nakamura Y, et al.
Stem Cell Res Ther
. 2024 Dec;
15(1):485.
PMID: 39696485
Background: Adipose-derived stem cells (ADSCs) are widely used in the field of regenerative medicine because of their various functions, including anti-inflammatory effects. ADSCs are considered to exert their anti-inflammatory effects...
2.
Sunatani Y, Sakasai R, Matsui T, Iwabuchi K
Biochem Biophys Res Commun
. 2024 Oct;
734:150776.
PMID: 39368367
The regulation of intracellular reactive oxygen species (ROS) levels is important for maintaining the self-renewal ability of neural stem/progenitor cells (NSCs). In this study, we demonstrate that 53BP1, a DNA...
3.
Sakasai R, Matsui T, Sunatani Y, Iwabuchi K
Biochem Biophys Res Commun
. 2023 May;
668:42-48.
PMID: 37244033
Camptothecin (CPT) exhibits strong cytotoxicity by inducing DNA double-strand breaks (DSBs) through DNA replication. Unlike radiation-induced DSBs, which have two DNA ends, CPT-induced DSBs are considered to have only one...
4.
Sakasai R, Wakasugi M, Matsui T, Sunatani Y, Saijo M, Matsunaga T, et al.
DNA Repair (Amst)
. 2022 Mar;
113:103318.
PMID: 35325630
DNA-damaging anti-cancer drugs are used clinically to induce cell death by causing DNA strand breaks or DNA replication stress. Camptothecin (CPT) and cisplatin are commonly used anti-cancer drugs, and their...
5.
Shibata T, Ikawa M, Sakasai R, Ishigaki Y, Kiyokawa E, Iwabuchi K, et al.
Mech Ageing Dev
. 2021 Apr;
196:111492.
PMID: 33862037
Tropomyosin (Tpm) 1 and 2 are important in the epithelial mesenchymal transition of lens epithelial cells; however, the effect of Tpm1 depletion during aging remains obscure. We analyzed the age-related...
6.
Watanabe A, Togi M, Koya T, Taniguchi M, Sakamoto T, Iwabuchi K, et al.
Genes Cells
. 2021 Mar;
26(5):313-327.
PMID: 33662167
As the sentinels of innate and adaptive immune system, dendritic cells (DCs) have been considered to hold a great promise for medical application. Among the diverse types of DCs, monocyte-derived...
7.
Fujii A, Sunatani Y, Furuichi K, Fujimoto K, Adachi H, Iwabuchi K, et al.
Sci Rep
. 2020 Dec;
10(1):22206.
PMID: 33335142
Collagen type VI (COL6) deposition occurs in various glomerular diseases, causing serious pathological damage like nodular lesions. However, the mechanisms underlying the deposition of COL6 remain unclear. In renal biopsy...
8.
Matsui M, Sakasai R, Abe M, Kimura Y, Kajita S, Torii W, et al.
Oncogenesis
. 2020 Jun;
9(6):60.
PMID: 32541651
The nucleus of mammalian cells is compartmentalized by nuclear bodies such as nuclear speckles, however, involvement of nuclear bodies, especially nuclear speckles, in DNA repair has not been actively investigated....
9.
Okuda K, Watanabe N, Hashimoto M, Doai M, Kawai Y, Takahashi T, et al.
Appl Radiat Isot
. 2019 Sep;
154:108890.
PMID: 31525597
DNA double-strand breaks (DSBs) of peripheral blood lymphocyte were prospectively assessed in 9 patients who were injected with Tl-chloride and I-beta-methyl-p-iodophenyl-pentadecanoic acid in dual-isotope imaging. Phosphorylated H2AX (γH2AX) was used...
10.
Sunatani Y, Kamdar R, Sharma M, Matsui T, Sakasai R, Hashimoto M, et al.
Exp Cell Res
. 2017 Dec;
362(2):450-460.
PMID: 29233683
X-ray repair cross-complementing group 4 (XRCC4), a repair protein for DNA double-strand breaks, is cleaved by caspases during apoptosis. In this study, we examined the role of XRCC4 in apoptosis....