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Kung-Yee Liang

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Articles 73
Citations 3419
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Recent Articles
1.
Chen Y, Liang K, Tong P, Beaty T, Barnes K, Kao W
Stat Methods Med Res . 2020 May; 29(11):3153-3165. PMID: 32393154
The case-control study design is one of the main tools for detecting associations between genetic markers and diseases. It is well known that population substructure can lead to spurious association...
2.
Gerstenblith T, Jaramillo-Huff A, Ruutiainen T, Nestadt P, Samuels J, Grados M, et al.
Compr Psychiatry . 2019 Sep; 94:152123. PMID: 31518848
Background: This study addresses the strength of associations between trichotillomania (TTM) and other DSM-IV Axis I conditions in a large sample (n = 2606) enriched for familial obsessive-compulsive disorder (OCD),...
3.
Di C, Chan K, Zheng C, Liang K
Commun Stat Theory Methods . 2018 May; 46(18):9092-9100. PMID: 29725157
Parametric and semiparametric mixture models have been widely used in applications from many areas, and it is often of interest to test homogeneity in these models. However, hypothesis testing is...
4.
Liu L, Guo C, Lee W, Chen L, Hwang A, Lin M, et al.
Sci Rep . 2017 Apr; 7:46417. PMID: 28397814
Frailty is a well-recognized geriatric syndrome with various definitions and conceptual frameworks. This study aimed to use latent class analysis to discover potential subtypes of pre-frail and frail older people....
5.
Marshall C, Howrigan D, Merico D, Thiruvahindrapuram B, Wu W, Greer D, et al.
Nat Genet . 2016 Nov; 49(1):27-35. PMID: 27869829
Copy number variants (CNVs) have been strongly implicated in the genetic etiology of schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has been hampered by limited...
6.
Chien L, Chiu Y, Liang K, Chuang L
Biostatistics . 2014 Dec; 16(2):222-39. PMID: 25481194
The genetic basis of complex diseases often involves multiple causative loci. Under such a disease etiology, assuming one disease locus in linkage disequilibrium mapping is likely to induce bias and...
7.
Ripke S, ODushlaine C, Chambert K, Moran J, Kahler A, Akterin S, et al.
Nat Genet . 2013 Aug; 45(10):1150-9. PMID: 23974872
Schizophrenia is an idiopathic mental disorder with a heritable component and a substantial public health impact. We conducted a multi-stage genome-wide association study (GWAS) for schizophrenia beginning with a Swedish...
8.
Wang P, Wang H, Wu-Chou Y, Ye X, Huang S, Shi B, et al.
Beijing Da Xue Xue Bao Yi Xue Ban . 2013 Jun; 45(3):352-8. PMID: 23774909
Objective: To explore the association between 18 candidate genes encoding enzymes on the folate/homocysteine metabolism pathway and non-syndromic cleft lip with or without cleft palate (NSCL/P) in Chinese populations. Methods:...
9.
Shihab H, Meoni L, Chu A, Wang N, Ford D, Liang K, et al.
Circulation . 2012 Nov; 126(25):2983-9. PMID: 23151344
Background: The obesity-hypertension link over the life course has not been well characterized, although the prevalence of obesity and hypertension is increasing in the United States. Methods And Results: We...
10.
Chen Y, Liang K
Biometrika . 2012 Jul; 97(3):603-620. PMID: 22822249
This paper considers the asymptotic distribution of the likelihood ratio statistic T for testing a subset of parameter of interest θ, θ = (γ, η), H(0) : γ = γ(0),...