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Kun-Tze Chen

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Articles 14
Citations 108
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Recent Articles
1.
Chen K, Shen H, Lu C
BMC Syst Biol . 2019 Jan; 12(Suppl 9):139. PMID: 30598087
Background: One of the important steps in the process of assembling a genome sequence from short reads is scaffolding, in which the contigs in a draft genome are ordered and...
2.
Chen K, Lu C
Nucleic Acids Res . 2018 May; 46(W1):W55-W59. PMID: 29733393
CSAR-web is a web-based tool that allows the users to efficiently and accurately scaffold (i.e. order and orient) the contigs of a target draft genome based on a complete or...
3.
Yen C, Lin J, Chen K, Lu C
BMC Bioinformatics . 2018 Jan; 18(Suppl 16):574. PMID: 29297283
Background: RNA molecules have been known to play a variety of significant roles in cells. In principle, the functions of RNAs are largely determined by their three-dimensional (3D) structures. As...
4.
Chen K, Liu C, Huang S, Shen H, Shieh Y, Chiu H, et al.
Bioinformatics . 2017 Oct; 34(1):109-111. PMID: 28968788
Summary: Advances in next generation sequencing have generated massive amounts of short reads. However, assembling genome sequences from short reads still remains a challenging task. Due to errors in reads...
5.
Chen K, Chen C, Shen H, Liu C, Huang S, Lu C
BMC Bioinformatics . 2017 Feb; 17(Suppl 17):469. PMID: 28155633
Background: A draft genome assembled by current next-generation sequencing techniques from short reads is just a collection of contigs, whose relative positions and orientations along the genome being sequenced are...
6.
Yang C, Shih C, Chen K, Lee P, Tsai P, Lin J, et al.
Nucleic Acids Res . 2016 May; 44(W1):W328-32. PMID: 27185896
Since its first release in 2010, iPARTS has become a valuable tool for globally or locally aligning two RNA 3D structures. It was implemented by a structural alphabet (SA)-based approach,...
7.
Lu C, Chen K, Huang S, Chiu H
BMC Bioinformatics . 2014 Nov; 15:381. PMID: 25431302
Background: Next generation sequencing technology has allowed efficient production of draft genomes for many organisms of interest. However, most draft genomes are just collections of independent contigs, whose relative positions...
8.
Li C, Chen K, Lu C
BMC Bioinformatics . 2013 Jun; 14 Suppl 5:S9. PMID: 23734866
The techniques of next generation sequencing allow an increasing number of draft genomes to be produced rapidly in a decreasing cost. However, these draft genomes usually are just partially sequenced...
9.
Huang K, Chen K, Lu C
BMC Genomics . 2012 Feb; 12 Suppl 3:S26. PMID: 22369173
Background: Genome rearrangements are studied on the basis of genome-wide analysis of gene orders and important in the evolution of species. In the last two decades, a variety of rearrangement...
10.
Liu Y, Yang C, Chen K, Wang J, Cheng M, Chung J, et al.
Nucleic Acids Res . 2011 Jun; 39(Web Server issue):W45-9. PMID: 21624889
R3D-BLAST is a BLAST-like search tool that allows the user to quickly and accurately search against the PDB for RNA structures sharing similar substructures with a specified query RNA structure....