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Kuang-Yu Chou

Explore the profile of Kuang-Yu Chou including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 446
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Recent Articles
11.
Tsai T, Chen P, Lin Y, Chou K, Chen H, Ho C, et al.
Environ Toxicol . 2019 Oct; 35(1):47-54. PMID: 31587482
Benzyl isothiocyanate (BITC), a bioactive natural product present in cruciferous vegetables, has been proved to prevent cancer progression through various mechanisms. In our previous report, we proved that BITC exhibits...
12.
Tsai T, Lin J, Lin Y, Chou K, Chen H, Ho C, et al.
Biosci Rep . 2019 Jul; 39(9). PMID: 31341011
Bladder cancer (BC) is the second most common urologic malignancy and the ninth most common malignancy worldwide. Surgical resection is the mainstay of treatment for patients with early-stage disease, whereas...
13.
Lin J, Tsai T, Lin Y, Chen H, Chou K, Hwang T
Int J Oncol . 2019 Apr; 54(6):2106-2116. PMID: 30942430
Benzyl isothiocyanate (BITC) is known for its pharmacological properties against malignant neoplasm, including bladder cancer (BC). The current study investigated microRNAs (miRNA or miR) expression profiles with an emphasis on...
14.
Chen H, Lin J, Tsai T, Lin Y, Chou K, Hwang T
Am J Chin Med . 2018 Oct; :1-19. PMID: 30284468
Allyl isothiocyanate (AITC), one of the most widely studied phytochemicals, inhibits the survival of human prostate cancer cells while minimally affecting normal prostate epithelial cells. Our study demonstrates the mechanism...
15.
Tsai T, Lin J, Chou K, Lin Y, Chen H, Hwang T
Onco Targets Ther . 2018 Jan; 11:239-252. PMID: 29379304
Introduction: miR-99a-5p, known to play an important role in mammalian target of rapamycin (mTOR) regulation, is downregulated in human bladder cancer. The study aimed to investigate the anticancer activity of...
16.
Lin Y, Lin J, Tsai T, Chen H, Chou K, Yang S, et al.
Sci Rep . 2017 Oct; 7(1):14103. PMID: 29074848
Human bladder cancer (BC) cells exhibit a high basal level of autophagic activity with accumulation of acridine-orange(AO)-stained acidic vesicular organelles. The rapid AO relocalization was observed in treated BC cells...
17.
Lin J, Lin Y, Tsai T, Chen H, Chou K, Hwang T
Drug Des Devel Ther . 2017 May; 11:1517-1533. PMID: 28553083
Purpose: Cisplatin-based chemotherapy is the first line treatment for several cancers including bladder cancer (BC). Autophagy induction has been implied to contribute to cisplatin resistance in ovarian cancer; and a...
18.
Lin Y, Lin J, Wen S, Yang S, Tsai T, Chen H, et al.
Kaohsiung J Med Sci . 2017 Apr; 33(5):215-223. PMID: 28433067
Chloroquine (CQ) and hydroxychloroquine (HCQ), two antimalarial drugs, are suggested to have potential anticancer properties. in the present study, we investigated the effects of CQ and HCQ on cell growth...
19.
Lin J, Tsai T, Yang S, Lin Y, Chen H, Chou K, et al.
Oncotarget . 2017 Apr; 8(12):20220-20234. PMID: 28423628
Benzyl isothiocyanate (BITC) in cruciferous plants, which are part of the human diet, has been shown to induce apoptosis in various types of cancer. In this study, we show that...
20.
Lin Y, Lin J, Tsai T, Chou K, Chen H, Hwang T
Asian J Surg . 2016 Aug; 40(5):396-406. PMID: 27519795
Background: Prostate cancer (PCa) is a leading cause of cancer-related death in men, which emphasizes the need for novel therapeutic approaches. Targeting microRNA (miRNA) has been considered as a therapeutic...