Alpha 2.0
Login Register
» Authors » Kuang-Yao Chen

Kuang-Yao Chen

Explore the profile of Kuang-Yao Chen including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 24
Citations 143
Followers 0
Related Specialties
Parasitology
Microbiology
Tropical Medicine
Top 10 Co-Authors
Lian-Chen Wang
Chien-Ju Cheng
Kai-Yuan Jhan
Cheng-Hsun Chiu
Yi-Ju Chen
Shih-Ming Jung
Chih-Jen Chou
Yi-Hsuan Lin
Shih-Hsin Chang
Kuo-Yang Huang
Published In
J Microbiol Immunol Infect
Parasitol Res
Parasit Vectors
Biomolecules
Biomed J
Affiliations
Soon will be listed here.
Recent Articles
1.
Extracellular vesicles from fifth-stage larval upregulate cholesterol biosynthesis and suppress NLRP2-associated inflammatory responses in mouse astrocytes
Cheng C, Wang L, Chu L, Chen K, Huang C, Lan K, et al.
mSystems . 2024 Dec; 10(1):e0101424. PMID: 39636121
is a zoonotic parasite that causes severe symptoms in humans, including eosinophilic meningitis and eosinophilic meningoencephalitis. Extracellular vesicles (EVs) derived from helminthes have been implicated in regulating host survival and...
2.
Identifying the function of novel cross-species microRNAs from the excretory-secretory products of Angiostrongylus cantonensis fifth-stage larvae
Chen K, Lin Y, Cheng C, Huang Y, Lin S, Chen C, et al.
J Microbiol Immunol Infect . 2024 Nov; 58(1):128-137. PMID: 39551634
Background: Angiostrongylus cantonensis is a significant foodborne zoonotic parasite that causes severe neuropathological damage and symptoms in humans. Excretory-secretory products (ESPs) play a pivotal role in elucidating host-parasite interactions and...
3.
Benzaldehyde stimulates autophagy via the sonic hedgehog signaling pathway in mouse brain astrocytes after treatment with Angiostrongylus cantonensis excretory-secretory products
Chen K, Cheng C, Chang Y, Lin Y, Huang Y, Lin S, et al.
Int J Parasitol Drugs Drug Resist . 2024 Aug; 26:100560. PMID: 39146602
Autophagy is a vital cellular process responsible for digesting various cytoplasmic organelles. This process plays a crucial role in maintaining cell survival and homeostasis, especially under conditions that cause nutrient...
4.
Doxycycline cotherapy with albendazole relieves neural function damage in C57BL/6 and BALB/c mice infected with Angiostrongylus cantonensis
Sofiyatun E, Chen K, Chou C, Lee H, Day Y, Chiang P, et al.
Biomed J . 2024 Apr; 48(1):100727. PMID: 38636898
Background: We investigated the effects of combination therapy albendazole and doxycycline in Angiostrongylus cantonensis-infected mice during early and late treatment. Materials And Methods: C57BL/6 and BALB/c mice were divided into...
5.
Protective effect of benzaldehyde combined with albendazole against brain injury induced by Angiostrongylus cantonensis infection in mice
Chen K, Cheng C, Chen Y, Chiu C, Wang L
Int J Antimicrob Agents . 2023 Sep; 62(5):106963. PMID: 37666435
Angiostrongylus cantonensis, also known as rat lungworm, is an important food-borne zoonotic parasite that causes severe neuropathological damage and symptoms, including eosinophilic meningitis and eosinophilic meningoencephalitis, in humans. At present,...
6.
The therapeutic effect of tanshinone IIA in mouse astrocytes after treatment with Angiostrongylus cantonensis fifth-stage larval excretory-secretory products
Chen K, Chen Y, Cheng C, Jhan K, Chiu C, Wang L
J Microbiol Immunol Infect . 2023 May; 56(4):853-862. PMID: 37147244
Background: Angiostrongylus cantonensis is an important food-borne zoonotic parasite that causes eosinophilic meningitis and meningoencephalitis in humans. Excretory-secretory products (ESPs) are valuable targets for studying host-parasite relationships. ESPs are composed...
7.
Improvements of cognitive functions in mice heavily infected by Angiostrongylus cantonensis after treatment with albendazole, dexamethasone, or co-therapy
Jhan K, Cheng C, Chou C, Jung S, Lai G, Chen K, et al.
J Microbiol Immunol Infect . 2022 Apr; 55(5):935-945. PMID: 35484079
Angiostrongylus cantonensis, the causative agent of human eosinophilic meningitis and eosinophilic meningoencepalitis, has been reported to cause cognitive impairments in the host. To determine whether drug treatment improves the cognitive...
8.
3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde enhance survival of mouse astrocytes treated with Angiostrongylus cantonensis young adults excretory/secretory products
Chen K, Chen Y, Cheng C, Jhan K, Chiu C, Wang L
Biomed J . 2022 Mar; 44(6 Suppl 2):S258-S266. PMID: 35300947
Background: Human cerebral angiostrongyliasis, induced by Angiostrongylus cantonensis, is an emerging disease in many parts of the world. A. cantonensis is also an important causative agent of eosinophilic meningitis and...
9.
Benzaldehyde Attenuates the Fifth Stage Larval Excretory-Secretory Product of -Induced Injury in Mouse Astrocytes via Regulation of Endoplasmic Reticulum Stress and Oxidative Stress
Chen K, Chen Y, Cheng C, Jhan K, Wang L
Biomolecules . 2022 Feb; 12(2). PMID: 35204678
Excretory-secretory products (ESPs) are the main research targets for investigating the hosts and helminths interaction. Parasitic worms can migrate to parasitic sites and avoid the host immune response by secreting...
10.
Co-Therapy of Albendazole and Dexamethasone Reduces Pathological Changes in the Cerebral Parenchyma of Th-1 and Th-2 Dominant Mice Heavily Infected with : Histopathological and RNA-seq Analyses
Jhan K, Cheng C, Jung S, Lai Y, Chen K, Wang L
Biomolecules . 2021 Apr; 11(4). PMID: 33917604
Administration of albendazole alone was not very suitable for the treatment of cerebral angiostrongyliasis. This study was designed to evaluate the effects of the co-therapy of this drug and dexamethasone...