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Kriti Agrawal

Explore the profile of Kriti Agrawal including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 716
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Recent Articles
1.
Sefik E, Xiao T, Chiorazzi M, Odell I, Zhang F, Agrawal K, et al.
Annu Rev Immunol . 2025 Feb; PMID: 40020225
Humanized mice, which carry a human hematopoietic and immune system, have greatly advanced our understanding of human immune responses and immunological diseases. These mice are created via the transplantation of...
2.
Yang J, Agrawal K, Stanley 3rd J, Stanley J, Li R, Jacobs N, et al.
bioRxiv . 2025 Feb; PMID: 39975288
HIV infection exerts profound and long-lasting neurodegenerative effects on the central nervous system (CNS) that can persist despite antiretroviral therapy (ART). Here, we used single-nucleus multiome sequencing to map the...
3.
Ament S, Campbell R, Lobo M, Receveur J, Agrawal K, Borjabad A, et al.
Mol Psychiatry . 2024 Jun; 29(12):3950-3961. PMID: 38879719
Substance use disorders (SUD) and drug addiction are major threats to public health, impacting not only the millions of individuals struggling with SUD, but also surrounding families and communities. One...
4.
Dong M, Agrawal K, Fan R, Sefik E, Flavell R, Kluger Y
bioRxiv . 2023 Nov; PMID: 38014345
How to identify true biological differences across samples while overcoming batch effects has been a persistent challenge in single-cell RNA-seq data analysis, hindering analyses across datasets for transferable biological findings....
5.
Lyu F, Burzynski C, Fang Y, Tal A, Chen A, Kisa J, et al.
JCI Insight . 2023 Oct; 8(21. PMID: 37815869
CXCR4 is a key regulator of the development of NK cells and DCs, both of which play an important role in early placental development and immune tolerance at the maternal-fetal...
6.
Odell I, Agrawal K, Sefik E, Odell A, Caves E, Kirkiles-Smith N, et al.
Proc Natl Acad Sci U S A . 2023 Sep; 120(37):e2306965120. PMID: 37669366
Fibrosis is regulated by interactions between immune and mesenchymal cells. However, the capacity of cell types to modulate human fibrosis pathology is poorly understood due to lack of a fully...
7.
Thomas J, Torok M, Agrawal K, Pfau T, Vu T, Lyberger J, et al.
Int J Mol Sci . 2022 Jul; 23(13). PMID: 35806069
The neonatal Fc receptor (FcRn) is responsible for recycling of IgG antibodies and albumin throughout the body. This mechanism has been exploited for pharmaceutic delivery across an array of diseases...
8.
Tang M, Tiwari S, Agrawal K, Tan M, Dang J, Tam T, et al.
Small . 2021 Jan; 17(15):e2006050. PMID: 33502104
Glioblastoma multiforme (GBM) is the most lethal primary brain tumor characterized by high cellular and molecular heterogeneity, hypervascularization, and innate drug resistance. Cellular components and extracellular matrix (ECM) are the...
9.
Wang L, Hui H, Agrawal K, Kang Y, Li N, Tang R, et al.
EMBO J . 2020 Sep; 39(20):e104514. PMID: 32964498
An impressive clinical success has been observed in treating a variety of cancers using immunotherapy with programmed cell death-1 (PD-1) checkpoint blockade. However, limited response in most patients treated with...
10.
Wang S, Zhang Q, Hui H, Agrawal K, Young Karris M, Rana T
Emerg Microbes Infect . 2020 Sep; 9(1):2333-2347. PMID: 32954948
Chronic infection with human immunodeficiency virus (HIV) can cause progressive loss of immune cell function, or exhaustion, which impairs control of virus replication. However, little is known about the development...