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Kristopher R Genschmer

Explore the profile of Kristopher R Genschmer including associated specialties, affiliations and a list of published articles. Areas
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Citations 317
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Recent Articles
1.
Plaisance E, Bergeron J, Bolyard M, Hathorne H, Graziano C, Hartzes A, et al.
Nutrients . 2024 Nov; 16(22). PMID: 39599743
Introduction: Cystic fibrosis transmembrane conductance regulator () modulators have greatly improved outcomes in persons with CF (pwCF); however, there is still significant heterogeneity in clinical responses, particularly with regard to...
2.
Madison M, Finley D, Genschmer K
J Leukoc Biol . 2024 Aug; 116(6):1220-1222. PMID: 39171927
No abstract available.
3.
Madison M, Margaroli C, Genschmer K, Russell D, Wells J, Sari E, et al.
Am J Respir Crit Care Med . 2023 Sep; 208(10):1115-1125. PMID: 37713301
Mounting evidence demonstrates a role for extracellular vesicles (EVs) in driving lung disorders, such as chronic obstructive pulmonary disease (COPD). Although cigarette smoke (CS) is the primary risk factor for...
4.
Genschmer K, Madison M, Viera L, Margaroli C, Gaggar A, Blalock J, et al.
Am J Physiol Lung Cell Mol Physiol . 2023 Apr; 324(5):L694-L699. PMID: 37014068
Chronic obstructive pulmonary disease (COPD) is characterized by lung extracellular matrix (ECM) remodeling that contributes to obstruction. This is driven, in part by extracellular vesicles (EVs) from activated neutrophils (PMNs),...
5.
Soto-Vazquez Y, Genschmer K
Front Pharmacol . 2023 Mar; 14:1081015. PMID: 36891265
Cardiopulmonary diseases span a wide breadth of conditions affecting both heart and lung, the burden of which is globally significant. Chronic pulmonary disease and cardiovascular disease are two of the...
6.
Oh J, Marques M, Xu X, Li J, Genschmer K, Phillips E, et al.
Transfusion . 2023 Feb; 63(3):586-600. PMID: 36752125
Background: The formation of extracellular vesicles (EVs) occurs during cold storage of RBCs. Transfusion of EVs may contribute to adverse responses in recipients receiving RBCs. However, EVs are poorly characterized...
7.
Margaroli C, Madison M, Viera L, Russell D, Gaggar A, Genschmer K, et al.
JCI Insight . 2022 Jan; 7(4). PMID: 35077395
Chronic obstructive pulmonary disease (COPD) is a debilitating chronic disease and the third-leading cause of mortality worldwide. It is characterized by airway neutrophilia, promoting tissue injury through release of toxic...
8.
Russell D, Genschmer K, Blalock J
Annu Rev Physiol . 2021 Nov; 84:631-654. PMID: 34724435
Chronic obstructive pulmonary disease (COPD) is a complex, heterogeneous, smoking-related disease of significant global impact. The complex biology of COPD is ultimately driven by a few interrelated processes, including proteolytic...
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Genschmer K, Vadesilho C, McDaniel L, Park S, Hale Y, Miyaji E, et al.
mSphere . 2019 Dec; 4(6). PMID: 31826968
Pneumococcal surface protein A (PspA) elicits antibody protective against lethal challenge by and is a candidate noncapsular antigen for inclusion in vaccines. Evaluation of immunity to PspA in human trials...