Kristin E Killoran
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Explore the profile of Kristin E Killoran including associated specialties, affiliations and a list of published articles.
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16
Citations
289
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Recent Articles
1.
Swanstrom A, Gorelick R, Welker J, Schmidt F, Lu B, Wang K, et al.
EBioMedicine
. 2023 Aug;
95:104764.
PMID: 37625266
Background: Long-acting subcutaneous lenacapavir (LEN), a first-in-class HIV capsid inhibitor approved by the US FDA for the treatment of multidrug-resistant HIV-1 with twice yearly dosing, is under investigation for HIV-1...
2.
Bissa M, Kim S, Galli V, Fourati S, Sarkis S, Arakelyan A, et al.
Nat Commun
. 2023 Feb;
14(1):575.
PMID: 36732510
The development of an effective vaccine to protect against HIV acquisition will be greatly bolstered by in-depth understanding of the innate and adaptive responses to vaccination. We report here that...
3.
Moles R, Sarkis S, Galli V, Omsland M, Artesi M, Bissa M, et al.
PLoS Pathog
. 2022 Apr;
18(4):e1010416.
PMID: 35377924
We investigated the impact of monocytes, NK cells, and CD8+ T-cells in primary HTLV-1 infection by depleting cell subsets and exposing macaques to either HTLV-1 wild type (HTLV-1WT) or to...
4.
Killoran K, Walsh C, Asher J, Tarleton M, Wilson S
J Am Assoc Lab Anim Sci
. 2021 Mar;
60(3):337-340.
PMID: 33731246
Anesthesia in rhesus macaques is required for many procedures. Although ketamine is the backbone of most anesthetic protocols, tolerance to the drug can develop, resulting in the need for higher...
5.
Killoran K, Kropp L, Lindrose A, Curtis H, Cook D, Mitre E
Clin Exp Allergy
. 2018 Dec;
49(4):484-494.
PMID: 30506823
Background: Rush desensitization can provide short-term tolerance to individuals who are allergic to certain medications in instances where other therapeutic interventions are limited. While rush desensitization (DS) is typically successful...
6.
Smith B, Killoran K, Xu J, Ayers J, Kendall L
J Am Assoc Lab Anim Sci
. 2018 May;
57(3):253-257.
PMID: 29784075
Prions are proteinaceous infectious agents that are highly resistant to denaturation. Sterilization of prion-contaminated mouse cages requires chemical agents and increased autoclave temperatures that damage traditional cages, thus increasing facility...
7.
Evans H, Killoran K, Mitre B, Morris C, Kim S, Mitre E
J Immunol
. 2015 Sep;
195(7):2973-84.
PMID: 26324775
In this study, we evaluated the effect chronic helminth infection has on allergic disease in mice previously sensitized to OVA. Ten weeks of infection with Litomosoides sigmodontis reduced immunological markers...
8.
Evans H, Killoran K, Mitre E
J Vis Exp
. 2014 Oct;
(92):e52005.
PMID: 25350839
Allergic responses are the result of the activation of mast cells and basophils, and the subsequent release of vasoactive and proinflammatory mediators. Exposure to an allergen in a sensitized individual...
9.
Killoran K, Miller A, Uray K, Weisbrodt N, Pautler R, Goyert S, et al.
Am J Physiol Gastrointest Liver Physiol
. 2014 Jan;
306(5):G445-53.
PMID: 24407593
Intestinal intussusception (ISS) commonly causes intestinal obstruction in children. One mechanism that has been proposed to cause ISS is inflammation-induced alteration of intestinal motility. We investigated whether innate inflammatory factors...
10.
Hubner M, Killoran K, Rajnik M, Wilson S, Yim K, Torrero M, et al.
PLoS Negl Trop Dis
. 2013 Jan;
6(12):e1970.
PMID: 23285308
Background: Chronic helminth infections induce a Th2 immune shift and establish an immunoregulatory milieu. As both of these responses can suppress Th1 immunity, which is necessary for control of Mycobacterium...