Kristian Thorlund
Overview
Explore the profile of Kristian Thorlund including associated specialties, affiliations and a list of published articles.
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154
Citations
11144
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Recent Articles
1.
Reis G, Augusto Dos Santos Moreira Silva E, Carla Medeiros Silva D, Thabane L, Santiago Ferreira T, Vitor Quirino Dos Santos C, et al.
Am J Clin Nutr
. 2024 Sep;
120(3):602-609.
PMID: 39232602
Background: Algae-derived nutraceuticals, such as spirulina, have been reported to have biological activities that may minimize clinical consequences to COVID-19 infections. Objectives: This study aimed to determine whether spirulina is...
2.
Reis G, Cancado Monteiro Savassi L, Santiago Ferreira T, Lanna Franca Reis L, Izabel Campos Simplicio M, Barra Ribeiro L, et al.
JAMA Netw Open
. 2024 May;
7(5):e2410335.
PMID: 38767921
Importance: Matched placebo interventions are complex and resource intensive. Recent evidence suggests matched placebos may not always be necessary. Previous studies have predominantly evaluated potential bias of nonmatched placebos (ie,...
3.
Arora P, Gupta A, Mackay E, Heeg B, Thorlund K
Value Health
. 2024 Apr;
27(8):999-1002.
PMID: 38636697
Objectives: The Inflation Reduction Act (IRA), enacted in 2022, brings substantial reforms to the US healthcare system, particularly regarding Medicare. A key aspect includes the introduction of Medicare price negotiation....
4.
Thorlund K, Duffield S, Popat S, Ramagopalan S, Gupta A, Hsu G, et al.
J Comp Eff Res
. 2024 Jan;
13(3):e230147.
PMID: 38205741
Development of medicines in rare oncologic patient populations are growing, but well-powered randomized controlled trials are typically extremely challenging or unethical to conduct in such settings. External control arms using...
5.
Thorlund K, Shephard C, Machado L, Bourgouin T, Hudson L, Ting E, et al.
Expert Rev Pharmacoecon Outcomes Res
. 2024 Jan;
24(3):331-342.
PMID: 38189086
Introduction: An avalanche of early stage cancer clinical trials is coming. The majority of these solely use surrogate outcomes that have not been validated against a target outcome of interest...
6.
The importance of appropriate selection of clinical endpoints in outpatient COVID-19 clinical trials
Thorlund K, Smith D, Linsell C, White N, Butler C, Boulware D, et al.
Commun Med (Lond)
. 2023 Apr;
3(1):53.
PMID: 37069219
Clinical trial endpoints must be carefully and intentionally selected so that the results of the trial can be used to inform policy- and decision-making. The relative importance of potential endpoints...
7.
Golchi S, Willard J, Pullenayegum E, Bassani D, Pell L, Thorlund K, et al.
Clin Trials
. 2022 Nov;
19(6):613-622.
PMID: 36408565
Introduction: Bayesian adaptive designs for clinical trials have gained popularity in the recent years due to the flexibility and efficiency that they offer. We consider the scenario where the outcome...
8.
Mills F, Reis G, Wilson L, Thorlund K, Forrest J, Guo C, et al.
Am J Trop Med Hyg
. 2022 Nov;
108(1):101-106.
PMID: 36379209
To date, two published randomized trials have indicated a clinical benefit of early treatment with fluvoxamine versus placebo for adults with symptomatic COVID-19. Using the results of the largest of...
9.
Kabbaha S, Milano A, Aldeyab M, Thorlund K
Br J Clin Pharmacol
. 2022 Sep;
89(1):49-60.
PMID: 36169097
Aims: Infliximab is a tumour necrosis factor-alpha inhibitor that is used to treat children with refractory Kawasaki disease (KD). Our purpose was to evaluate the safety and impact of infliximab...
10.
Smith E, Oakley E, He S, Zavala R, Ferguson K, Miller L, et al.
PLoS One
. 2022 Jun;
17(6):e0270150.
PMID: 35709239
We urgently need answers to basic epidemiological questions regarding SARS-CoV-2 infection in pregnant and postpartum women and its effect on their newborns. While many national registries, health facilities, and research...