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Kristian Pajtler

Explore the profile of Kristian Pajtler including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 444
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Recent Articles
1.
Hirsch S, Rahmanzade R, Grund K, Sutter C, Schramm K, Selt F, et al.
Acta Neuropathol . 2025 Mar; 149(1):25. PMID: 40085243
No abstract available.
2.
Obrecht-Sturm D, Schoof M, Eckhardt A, Mynarek M, Gilbert M, Aldape K, et al.
Neuro Oncol . 2024 Aug; 27(1):267-276. PMID: 39171767
Background: Ependymoma (EPN) is not a uniform disease but represents different disease types with biological and clinical heterogeneity. However, the pattern of when and where different types of EPN relapse...
3.
Schoot R, Orbach D, Minard Colin V, Alaggio R, Di Carlo D, Corradini N, et al.
JCO Precis Oncol . 2023 Oct; 7:e2300323. PMID: 37856763
Purpose: Inflammatory myofibroblastic tumors (IMTs) are often driven by anaplastic lymphoma kinase fusions and less frequently by alternative fusions such as . We describe the clinical characteristics, treatment approach, and...
4.
Obrecht D, Mynarek M, Stickan-Verfurth M, Bison B, Schuller U, Pajtler K, et al.
Klin Padiatr . 2023 May; 235(3):167-177. PMID: 37172610
Biological subtypes of ependymoma (EPN) have been introduced by the recent WHO classification and appear to have great impact on the clinical course, but have not yet found their way...
5.
Ellison D, Aldape K, Capper D, Fouladi M, Gilbert M, Gilbertson R, et al.
Brain Pathol . 2020 Jun; 30(5):863-866. PMID: 32502305
Advances in our understanding of the biological basis and molecular characteristics of ependymal tumors since the latest iteration of the World Health Organization (WHO) classification of CNS tumors (2016) have...
6.
Schulte J, Bachmann H, Brockmeyer B, Depreter K, Oberthur A, Ackermann S, et al.
Clin Cancer Res . 2011 Jun; 17(15):5082-92. PMID: 21632861
Purpose: Genomic alterations of the anaplastic lymphoma kinase (ALK) gene have been postulated to contribute to neuroblastoma pathogenesis. This study aimed to determine the interrelation of ALK mutations, ALK expression...
7.
Pajtler K, Bohrer A, Maurer J, Schorle H, Schramm A, Eggert A, et al.
J Vis Exp . 2010 Dec; (45). PMID: 21178955
The neural crest arises from the neuro-ectoderm during embryogenesis and persists only temporarily. Early experiments already proofed pluripotent progenitor cells to be an integral part of the neural crest(1). Phenotypically,...
8.
Schulte J, Schowe B, Mestdagh P, Kaderali L, Kalaghatgi P, Schlierf S, et al.
Int J Cancer . 2010 May; 127(10):2374-85. PMID: 20473924
For neuroblastoma, the most common extracranial tumour of childhood, identification of new biomarkers and potential therapeutic targets is mandatory to improve risk stratification and survival rates. MicroRNAs are deregulated in...
9.
Schulte J, Lim S, Schramm A, Friedrichs N, Koster J, Versteeg R, et al.
Cancer Res . 2009 Feb; 69(5):2065-71. PMID: 19223552
Aberrant epigenetic changes in DNA methylation and histone acetylation are hallmarks of most cancers, whereas histone methylation was previously considered to be irreversible and less versatile. Recently, several histone demethylases...