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Kristian Leite

Explore the profile of Kristian Leite including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 40
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Recent Articles
1.
Garg P, Wurtz F, Hobbie F, Buttgereit K, Aich A, Leite K, et al.
J Neuroinflammation . 2024 Feb; 21(1):62. PMID: 38419079
Background: Presence of autoantibodies against α-synuclein (α-syn AAb) in serum of the general population has been widely reported. That such peripheral factors may be involved in central nervous system pathophysiology...
2.
Leite K, Garg P, Spitzner F, Guerin Darvas S, Bahr M, Priesemann V, et al.
Front Mol Neurosci . 2022 Jun; 15:868790. PMID: 35721317
α-synuclein (α-Syn) is intimately linked to synucleinopathies like Parkinson's disease and dementia with Lewy bodies. However, the pathophysiological mechanisms that are triggered by this protein are still largely enigmatic. α-Syn...
3.
Psol M, Guerin Darvas S, Leite K, Mahajani S, Bahr M, Kugler S
Hum Mol Genet . 2021 Mar; 30(3-4):247-264. PMID: 33760043
Beta (ß)-synuclein (ß-Syn) has long been considered to be an attenuator for the neuropathological effects caused by the Parkinson's disease-related alpha (α)-synuclein (α-Syn) protein. However, recent studies demonstrated that overabundant...
4.
Sirp A, Leite K, Tuvikene J, Nurm K, Sepp M, Timmusk T
Sci Rep . 2020 Oct; 10(1):18424. PMID: 33116252
The CTG trinucleotide repeat (TNR) expansion in Transcription factor 4 (TCF4) intron 3 is the main cause of Fuchs' endothelial corneal dystrophy (FECD) and may confer an increased risk of...
5.
Raina A, Leite K, Guerin S, Mahajani S, Chakrabarti K, Voll D, et al.
J Neurochem . 2020 Jul; 156(5):674-691. PMID: 32730640
A contribution of α-Synuclein (α-Syn) to etiology of Parkinson´s disease (PD) and Dementia with Lewy bodies (DLB) is currently undisputed, while the impact of the closely related β-Synuclein (β-Syn) on...
6.
Tolo J, Taschenberger G, Leite K, Stahlberg M, Spehlbrink G, Kues J, et al.
Front Mol Neurosci . 2018 Mar; 11:49. PMID: 29563864
α-Synuclein (α-Syn) is intimately linked to the etiology of Parkinson's Disease, as mutations and even subtle increases in gene dosage result in early onset of the disease. However, how this...