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Kristen Purrington

Explore the profile of Kristen Purrington including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 21
Citations 777
Followers 0
Related Specialties
Oncology
Genetics
Molecular Biology
Top 10 Co-Authors
Peter A Fasching
Kamila Czene
Matthias W Beckmann
Per Hall
Jacques Simard
Loic Le Marchand
Douglas F Easton
Melissa C Southey
Mark Manning
Stig E Bojesen
Published In
Hum Mol Genet
Soc Sci Med
Cancer Res
Am J Hum Genet
Carcinogenesis
Affiliations
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Recent Articles
11.
Explaining between-race differences in African-American and European-American women's responses to breast density notification
Manning M, Albrecht T, Yilmaz-Saab Z, Penner L, Norman A, Purrington K
Soc Sci Med . 2017 Nov; 195:149-158. PMID: 29102420
Background: Prior research shows between-race differences in women's knowledge and emotions related to having dense breasts, thus suggesting that between-race differences in behavioral decision-making following receipt of breast density (BD)...
12.
The effect of genetic variants on the relationship between statins and breast cancer in postmenopausal women in the Women's Health Initiative observational study
Bock C, Jay A, Dyson G, Beebe-Dimmer J, Cote M, Hou L, et al.
Breast Cancer Res Treat . 2017 Oct; 167(3):741-749. PMID: 29063981
Purpose: Statins have been postulated to have chemopreventive activity against breast cancer. We evaluated whether germline genetic polymorphisms modified the relationship between statins and breast cancer risk using data from...
13.
Influences of race and breast density on related cognitive and emotion outcomes before mandated breast density notification
Manning M, Albrecht T, Yilmaz-Saab Z, Shultz J, Purrington K
Soc Sci Med . 2016 Oct; 169:171-179. PMID: 27733299
Rationale: Many states have adopted laws mandating breast density (BD) notification for applicable women; however, very little is known about what women knew or felt about BD and related breast...
14.
Between-race differences in the effects of breast density information and information about new imaging technology on breast-health decision-making
Manning M, Purrington K, Penner L, Duric N, Albrecht T
Patient Educ Couns . 2016 Feb; 99(6):1002-10. PMID: 26847421
Objectives: Some US states have mandated that women be informed when they have dense breasts; however, little is known about how general knowledge about breast density (BD) affects related health...
15.
Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures
Stone J, Thompson D, Dos Santos Silva I, Scott C, Tamimi R, Lindstrom S, et al.
Cancer Res . 2015 Apr; 75(12):2457-67. PMID: 25862352
Mammographic density measures adjusted for age and body mass index (BMI) are heritable predictors of breast cancer risk, but few mammographic density-associated genetic variants have been identified. Using data for...
16.
Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer
Kabisch M, Lorenzo Bermejo J, Dunnebier T, Ying S, Michailidou K, Bolla M, et al.
Carcinogenesis . 2015 Jan; 36(2):256-71. PMID: 25586992
The chromosomal passenger complex (CPC) plays a pivotal role in the regulation of cell division. Therefore, inherited CPC variability could influence tumor development. The present candidate gene approach investigates the...
17.
Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk
Lin W, Camp N, Ghoussaini M, Beesley J, Michailidou K, Hopper J, et al.
Hum Mol Genet . 2014 Aug; 24(1):285-98. PMID: 25168388
Previous studies have suggested that polymorphisms in CASP8 on chromosome 2 are associated with breast cancer risk. To clarify the role of CASP8 in breast cancer susceptibility, we carried out...
18.
Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium
Milne R, Burwinkel B, Michailidou K, Arias-Perez J, Zamora M, Menendez-Rodriguez P, et al.
Hum Mol Genet . 2014 Jun; 23(22):6096-111. PMID: 24943594
Candidate variant association studies have been largely unsuccessful in identifying common breast cancer susceptibility variants, although most studies have been underpowered to detect associations of a realistic magnitude. We assessed...
19.
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
Meyer K, OReilly M, Michailidou K, Carlebur S, Edwards S, French J, et al.
Am J Hum Genet . 2013 Dec; 93(6):1046-60. PMID: 24290378
The 10q26 locus in the second intron of FGFR2 is the locus most strongly associated with estrogen-receptor-positive breast cancer in genome-wide association studies. We conducted fine-scale mapping in case-control studies...
20.
Identification of new genetic susceptibility loci for breast cancer through consideration of gene-environment interactions
Schoeps A, Rudolph A, Seibold P, Dunning A, Milne R, Bojesen S, et al.
Genet Epidemiol . 2013 Nov; 38(1):84-93. PMID: 24248812
Genes that alter disease risk only in combination with certain environmental exposures may not be detected in genetic association analysis. By using methods accounting for gene-environment (G × E) interaction,...