Kristala L J Prather
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Explore the profile of Kristala L J Prather including associated specialties, affiliations and a list of published articles.
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82
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1847
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Recent Articles
1.
Bannister K, Prather K
Metab Eng
. 2024 Sep;
86:124-134.
PMID: 39313110
Polyhydroxyalkanoates (PHAs) are renewably-derived, microbial polyesters composed of hydroxy acids (HAs). Demand for sustainable plastics alternatives, combined with the unfavorable thermal properties exhibited by some PHAs, motivates the discovery of...
2.
Song Y, Prather K
Curr Opin Chem Biol
. 2024 Jul;
81:102493.
PMID: 38971129
Growing environmental concerns and the urgency to address climate change have increased demand for the development of sustainable alternatives to fossil-derived fuels and chemicals. Microbial systems, possessing inherent biosynthetic capabilities,...
3.
Ni C, Prather K
Metab Eng
. 2024 Jan;
82:41-48.
PMID: 38185463
The use of waste streams and other renewable feedstocks in microbial biosynthesis has long been a goal for metabolic engineers. Microbes can utilize the substrate mixtures found in waste streams,...
4.
Nash J, Prather K
J Ind Microbiol Biotechnol
. 2023 Jun;
50(1).
PMID: 37327078
One-sentence Summary: In this work, a transcription-factor biosensor was investigated for its potential to screen a library of myo -inositol oxygenase variants while seeking to mitigate the impact the production...
5.
Ma X, Liang H, Pan Q, Prather K, Sinskey A, Stephanopoulos G, et al.
J Agric Food Chem
. 2022 Mar;
70(11):3512-3520.
PMID: 35286075
Engineering microbes to produce isoprenoids can be limited by the competition between product formation and cell growth because biomass and isoprenoids are naturally derived from central metabolism. Recently, a two-step...
6.
Vila-Santa A, Mendes F, Ferreira F, Prather K, Mira N
J Fungi (Basel)
. 2021 Dec;
7(12).
PMID: 34947002
Microbially produced carboxylic acids (CAs) are considered key players in the implementation of more sustainable industrial processes due to their potential to replace a set of oil-derived commodity chemicals. Most...
7.
Kaczmarek J, Prather K
J Ind Microbiol Biotechnol
. 2021 Aug;
48(9-10).
PMID: 34347108
The development of fast and affordable microbial production from recombinant pathways is a challenging endeavor, with targeted improvements difficult to predict due to the complex nature of living systems. To...
8.
Ni C, Fox K, Prather K
Biotechnol J
. 2021 May;
17(3):e2000433.
PMID: 34050620
Microbes can facilitate production of valuable chemicals more sustainably than traditional chemical processes in many cases: they utilize renewable feedstocks, require less energy intensive process conditions, and perform a variety...
9.
Almeida B, Kaczmarek J, Figueiredo P, Prather K, Carvalho A
NAR Genom Bioinform
. 2021 May;
3(2):lqab033.
PMID: 33987533
The development of new synthetic biology circuits for biotechnology and medicine requires deeper mechanistic insight into allosteric transcription factors (aTFs). Here we studied the aTF UxuR, a homodimer of two...
10.
Haslinger K, Hackl T, Prather K
Cell Chem Biol
. 2021 May;
28(6):876-886.e4.
PMID: 33957079
O-Methyltransferases are ubiquitous enzymes involved in biosynthetic pathways for secondary metabolites such as bacterial antibiotics, human catecholamine neurotransmitters, and plant phenylpropanoids. While thousands of putative O-methyltransferases are found in sequence...